Description

5-Bromo-3-methoxypyrazine-2-carbaldehyde (CAS No. 2288709-85-1) is a high-purity, specialized heterocyclic aldehyde with the molecular formula C₆H₅BrN₂O₂. This compound features a pyrazine core substituted with a bromo group at the 5-position, a methoxy group at the 3-position, and a reactive formyl group at the 2-position, making it a versatile building block for pharmaceutical, agrochemical, and material science research. Its unique structure enables applications in cross-coupling reactions, nucleophilic additions, and as a precursor for synthesizing complex heterocycles. Available in >95% purity (HPLC), it is supplied as a crystalline solid with strict quality control to ensure reproducibility in sensitive reactions. Ideal for medicinal chemistry, catalysis, and functional material development.

Properties

• CAS Number: 2288709-85-1
• Complexity: 145
• IUPAC Name: 5-bromo-3-methoxy-pyrazine-2-carbaldehyde
• InChI: InChI=1S/C6H5BrN2O2/c1-11-6-4(3-10)8-2-5(7)9-6/h2-3H,1H3
• InChI Key: ZIMREOLNVRMGST-UHFFFAOYSA-N
• Exact Mass: 215.95344
• Molecular Formula: C6H5BrN2O2
• Molecular Weight: 217.02
• SMILES: COC1=NC(=CN=C1C=O)Br
• Topological: 52.1
• Monoisotopic Mass: 215.95344
• Synonyms: 5-Bromo-3-methoxypyrazine-2-carbaldehyde, 2288709-85-1, MFCD31744459, SCHEMBL21274185, SY288597, 5-bromo-3-methoxy-pyrazine-2-carbaldehyde, 5-bromo-3-methoxy-2-Pyrazinecarboxaldehyde, DB-413695, G18626

5-Bromo-3-methoxypyrazine-2-carbaldehyde serves as a key intermediate in the synthesis of bioactive molecules, particularly in drug discovery for kinase inhibitors and antimicrobial agents. Its aldehyde group facilitates Schiff base formation, while the bromo moiety enables Suzuki-Miyaura cross-coupling reactions. Researchers utilize this compound to construct pyrazine-based scaffolds for optoelectronic materials due to its electron-deficient aromatic system. It is also employed in ligand design for transition-metal catalysis.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.