Description
5-Bromo-2-methoxypyridine (CAS No. 13472-85-0) is a high-purity heterocyclic compound with the molecular formula C6H6BrNO. This fine chemical is widely utilized as a key intermediate in pharmaceutical synthesis, agrochemical production, and advanced material research. The product is supplied as a white to off-white crystalline powder with a guaranteed purity of ≥95%, ensuring consistency for critical applications. Our 5-Bromo-2-methoxypyridine undergoes rigorous QC testing including HPLC, NMR, and mass spectrometry analysis to meet the exacting standards of research laboratories and industrial processes. Proper storage conditions (2-8°C in airtight containers) maintain stability and shelf life.
This brominated pyridine derivative is particularly valuable for:
- Transition metal-catalyzed cross-coupling reactions
- Building block for kinase inhibitors and other bioactive molecules
- Ligand synthesis in coordination chemistry
- Material science applications
Available in research quantities (100mg to 1g) and bulk orders (25g+), with customizable packaging options including amber glass vials and nitrogen-flushed foil bags.
Properties
- CAS Number: 13472-85-0
- Complexity: 89.1
- IUPAC Name: 5-bromo-2-methoxy-pyridine
- InChI: InChI=1S/C6H6BrNO/c1-9-6-3-2-5(7)4-8-6/h2-4H,1H3
- InChI Key: XADICJHFELMBGX-UHFFFAOYSA-N
- Exact Mass: 186.96328
- Molecular Formula: C6H6BrNO
- Molecular Weight: 188.02
- SMILES: COC1=NC=C(C=C1)Br
- Topological: 22.1
- Monoisotopic Mass: 186.96328
- Synonyms: 5-Bromo-2-methoxypyridine, 13472-85-0, DTXSID60370559, DTXCID90321594, 603-856-9, 2-methoxy-5-bromopyridine, PYRIDINE, 5-BROMO-2-METHOXY-, MFCD01318952, 3-BROMO-6-METHOXYPYRIDINE, 5-Bromo-2-methoxy-pyridine, 5-bromo-2-methoxy pyridine, 2-methoxy-5-bromo-pyridine, perampanel Impurity 50, 5-brom-2-methoxypyridin, 5-bromo-2methoxypyridine, 5-bromo-2methoxy-pyridine, SCHEMBL130166, SCHEMBL314660, 5-bromo-2-(methyloxy)pyridine, SCHEMBL1098500, 5-Bromo-2-methoxypyridine, 95%, BCP23292, CS-D0943, SBB059393, AKOS005145726, AB08771, AC-5132, FB04226, PS-3525, 2-methoxy-5-bromopyridine, picric acid, AC-23014, HY-32756, SY007569, DB-023727, B2398, NS00126538, ST50408791, EN300-97020, AC-907/25004518, Z808608370, InChI=1/C6H6BrNO/c1-9-6-3-2-5(7)4-8-6/h2-4H,1H
5-Bromo-2-methoxypyridine serves as a versatile building block in medicinal chemistry, particularly for constructing pyridine-containing drug scaffolds. The bromine moiety enables efficient palladium-catalyzed coupling reactions (Suzuki, Stille, etc.) for structural diversification. Researchers employ this compound in developing CNS-active compounds and kinase inhibitors due to its balanced lipophilicity and hydrogen bonding capacity. The methoxy group provides both steric and electronic modulation of reactivity patterns during synthetic transformations.
Safety and Hazards
GHS Hazard Statements
- H315 (92.6%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (94.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (83.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (92.6%)
- Eye Irrit. 2 (94.4%)
- STOT SE 3 (83.3%)
If you are interested or have any questions, please contact us at support@atomfair.com
Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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