Description

5-Amino-2-chloropyridine (CAS No. 5350-93-6) is a high-purity heterocyclic organic compound with the molecular formula C₅H₅ClN₂ and IUPAC name 6-chloropyridin-3-amine. This fine chemical is a valuable building block in pharmaceutical, agrochemical, and material science research. The compound features a pyridine ring substituted with an amino group at the 5-position and a chloro group at the 2-position, offering versatile reactivity for nucleophilic substitution and cross-coupling reactions. Our product is rigorously tested to ensure ≥98% purity by HPLC, with detailed technical data available including NMR, FTIR, and mass spectrometry characterization. Supplied as a white to off-white crystalline powder, it is packaged under inert atmosphere to ensure stability and long shelf life. Suitable for use in medicinal chemistry, catalyst development, and as a precursor for more complex heterocyclic systems.

Properties

• CAS Number: 5350-93-6
• Complexity: 76.8
• IUPAC Name: 6-chloropyridin-3-amine
• InChI: InChI=1S/C5H5ClN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2
• InChI Key: QAJYCQZQLVENRZ-UHFFFAOYSA-N
• Exact Mass: 128.0141259
• Molecular Formula: C5H5ClN2
• Molecular Weight: 128.56
• SMILES: C1=CC(=NC=C1N)Cl
• Topological: 38.9
• Monoisotopic Mass: 128.0141259
• Synonyms: 5-Amino-2-chloropyridine, 5350-93-6, EINECS 226-322-3, NSC 81, DTXSID40201716, DTXCID70124207, 226-322-3, 6-chloropyridin-3-amine, 2-Chloro-5-aminopyridine, 3-Amino-6-chloropyridine, 3-Pyridinamine, 6-chloro-, MFCD00006243, 6-Chloro-pyridin-3-ylamine, 6-chloro-3-pyridylamine, 6-Chloro-3-pyridinamine, 5-amino-2-chloro pyridine, 386QR22KDZ, NSC-81, 5350-27-6, 2-chloro-5-amino pyridine, NSC81, 5amino-2-chloropyridine, 6-chloro-3-aminopyridine, 6-chloropyridine-3-amine, 6-chloro-pyridin-3-amine, 6-chloropyridin-3-ylamine, 2-chloro-5-amino-pyridine, 3-amino-6-chloro-pyridine, 5-amino-2-chloro-pyridine, 6-chloro-3-amino pyridine, SCHEMBL9593, 6-Chloro-3-pyridinamine #, UNII-386QR22KDZ, Pyridine, 5-amino-2-chloro-, SCHEMBL1274683, SCHEMBL11728802, SCHEMBL21380941, SCHEMBL28249907, 5-Amino-2-chloropyridine, 98%, CHEBI:194601, BCP22171, STR02641, BBL011061, SBB004234, STK802240, AKOS000121100, AB00661, AC-1214, CS-W007481, HY-W007481, PS-3660, SY009586, DB-024116, DB-031417, DB-332841, A1155, NS00032774, ST50949409, EN300-34596, AC-907/25014053, F2145-0706, Z335436282, InChI=1/C5H5ClN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H

Application

5-Amino-2-chloropyridine serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antiviral agents. In agrochemical research, it is utilized for creating novel pesticides and herbicides due to its bioactive pyridine core. The compound’s dual functionality makes it valuable for palladium-catalyzed cross-coupling reactions in material science applications.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (98.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (98.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.