Description

5-Amino-2-chlorobenzenesulfonamide (CAS No. 2015-19-2) is a high-purity sulfonamide derivative with the molecular formula C₆H₇ClN₂O₂S. This compound is widely utilized in pharmaceutical research, organic synthesis, and as a key intermediate in the development of bioactive molecules. Its well-defined structure, characterized by an amino group and a chloro substituent on the benzene ring, makes it a versatile building block for medicinal chemistry applications. Available in >98% purity, this product is rigorously tested for quality and consistency, ensuring reliable performance in demanding research environments. Suitable for laboratory use only.

Properties

• CAS Number: 2015-19-2
• Complexity: 249
• IUPAC Name: 5-amino-2-chloro-benzenesulfonamide
• InChI: InChI=1S/C6H7ClN2O2S/c7-5-2-1-4(8)3-6(5)12(9,10)11/h1-3H,8H2,(H2,9,10,11)
• InChI Key: FDDSVQLOFIBCDH-UHFFFAOYSA-N
• Exact Mass: 205.9916763
• Molecular Formula: C6H7ClN2O2S
• Molecular Weight: 206.65
• SMILES: C1=CC(=C(C=C1N)S(=O)(=O)N)Cl
• Topological: 94.6
• Monoisotopic Mass: 205.9916763
• Synonyms: 5-amino-2-chlorobenzenesulfonamide, Benzenesulfonamide, 5-amino-2-chloro-, 5-Amino-2-chlorobenzenesulphonamide, 2-Chloro-5-aminobenzenesulfonamide, 3-Aminosulfonyl-4-chloroaniline, Y6X4C839EF, DTXSID10173976, 2-CHLORO-5-AMINOBENZENESULPHONAMIDE, DTXCID2096467, 2015-19-2, EINECS 217-943-0, 5-amino-2-chlorobenzene-1-sulfonamide, 5-amino-2-chloro-benzenesulfonamide, MFCD00036102, UNII-Y6X4C839EF, CHEMBL499281, SCHEMBL1806724, SCHEMBL1806726, AKOS008115904, SB77444, BS-15892, DB-066071, CS-0157052, NS00026535, EN300-59084, D81724, Z359331400

5-Amino-2-chlorobenzenesulfonamide serves as a critical intermediate in the synthesis of sulfonamide-based pharmaceuticals, including antimicrobial and diuretic agents. Researchers employ this compound in structure-activity relationship (SAR) studies to optimize drug candidates targeting bacterial infections. Its reactive amino group enables further derivatization for the development of novel heterocyclic compounds. The chloro substituent enhances electrophilic reactivity, facilitating cross-coupling reactions in organic synthesis.

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