Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one C14H18BNO3 CAS 837392-64-0

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one (CAS No. 837392-64-0) is a high-purity boronic ester derivative with the molecular formula C14H18BNO3. This compound features a pinacol boronate group attached to an indolin-2-one scaffold, making it a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and compatibility with a wide range of functional groups make it ideal for pharmaceutical research, material science, and agrochemical development. Available in various quantities, this product is rigorously tested for purity (>95% by HPLC) and consistency, ensuring reliable performance in your laboratory applications. Store in a cool, dry place under inert atmosphere for prolonged shelf…

Category:

Description

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one (CAS No. 837392-64-0) is a high-purity boronic ester derivative with the molecular formula C14H18BNO3. This compound features a pinacol boronate group attached to an indolin-2-one scaffold, making it a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and compatibility with a wide range of functional groups make it ideal for pharmaceutical research, material science, and agrochemical development. Available in various quantities, this product is rigorously tested for purity (>95% by HPLC) and consistency, ensuring reliable performance in your laboratory applications. Store in a cool, dry place under inert atmosphere for prolonged shelf life.

Properties

  • CAS Number: 837392-64-0
  • Complexity: 380
  • IUPAC Name: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
  • InChI: InChI=1S/C14H18BNO3/c1-13(2)14(3,4)19-15(18-13)10-5-6-11-9(7-10)8-12(17)16-11/h5-7H,8H2,1-4H3,(H,16,17)
  • InChI Key: BXFPTCYBFJOZHJ-UHFFFAOYSA-N
  • Exact Mass: 259.1379736
  • Molecular Formula: C14H18BNO3
  • Molecular Weight: 259.11
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)NC(=O)C3
  • Topological: 47.6
  • Monoisotopic Mass: 259.1379736
  • Synonyms: 837392-64-0, 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)INDOLIN-2-ONE, 812-101-4, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydroindol-2-one, 2-Oxoindoline-5-boronic Acid Pinacol Ester, 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL) INDOLIN-2-ONE, OXINDOLE-5-BORONIC ACID, PINACOL ESTER, MFCD08669935, 1,3-Dihydroindol-2-one-5-boronic acid pinacol ester, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxindole, 1,3-Dihydroindol-2-one-5-boronicacidpinacol ester, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-indol-2-one, 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indol-2-one, Oxindole-5-boronic acid pinacol ester, SCHEMBL454535, DTXSID30620275, BXFPTCYBFJOZHJ-UHFFFAOYSA-N, BCP26669, 5-Oxindoleboronic Acid Pinacol Ester, 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydro-indol-2-one, AKOS015945124, PB11853, 2-Oxoindoline-5-boronicAcidPinacolEster, NCGC00662616-01, SY025029, DB-075972, CS-0044509, T3512, EN300-138961, P10616, W18973, 2-OXOINDOLIN-5-YLBORONIC ACID PINACOL ESTER, Z1171974296, 2-(Oxindole-5-yl)-4,4,5,5-Tetramethyl-1,3,2-dioxaborolane, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one, AldrichCPR, 1,3-Dihydro-indol-2-one-5-boronic acid pinacol ester;Oxindole-5-boronic acid, pinacol ester;5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indol-2-one

Application

This compound is widely used as a key intermediate in the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and other pharmaceutical agents. Its boronate ester functionality enables efficient cross-coupling reactions for constructing complex heterocyclic systems. Researchers also utilize it in the preparation of fluorescent dyes and organic electronic materials due to its stable yet reactive boronic ester group.

Safety and Hazards

GHS Hazard Statements

  • H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (50%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products