Description

5-(4-Methylpiperazin-1-yl)-2-nitroaniline (CAS No. 23491-48-7) is a high-purity nitroaniline derivative with the molecular formula C₁₁H₁₆N₄O₂. This compound features a methylpiperazine moiety and a nitroaniline core, making it a valuable intermediate for pharmaceutical and organic synthesis applications. It is supplied as a fine powder with ≥95% purity (HPLC), ensuring consistency for research and industrial use. Suitable for use in medicinal chemistry, drug discovery, and material science, this product is rigorously tested for quality, stability, and solubility. Store in a cool, dry place under inert conditions to maintain integrity.

Properties

• CAS Number: 23491-48-7
• Complexity: 273
• IUPAC Name: 5-(4-methylpiperazin-1-yl)-2-nitro-aniline
• InChI: InChI=1S/C11H16N4O2/c1-13-4-6-14(7-5-13)9-2-3-11(15(16)17)10(12)8-9/h2-3,8H,4-7,12H2,1H3
• InChI Key: MWLBMGPQZJDFKZ-UHFFFAOYSA-N
• Exact Mass: 236.12732577
• Molecular Formula: C11H16N4O2
• Molecular Weight: 236.27
• SMILES: CN1CCN(CC1)C2=CC(=C(C=C2)[N+](=O)[O-])N
• Topological: 78.3
• Monoisotopic Mass: 236.12732577
• Synonyms: 23491-48-7, 5-(4-methylpiperazin-1-yl)-2-nitroaniline, DTXSID20374997, DTXCID70326027, 673-328-0, 5-(4-Methylpiperazin-1-yl)-2-nitrophenylamine, 5-(4-methylpiperazino)-2-nitroaniline, 5-(4-Methyl-piperazin-1-yl)-2-nitro-phenylamine, MFCD00545964, CHEMBL1370863, 5-(4-methylpiperazin-1-yl)-2-nitrobenzenamine, 5-(4-Methyl-piperazin-1-yl)-2-nitroaniline, 5-(4-methylpiperazinyl)-2-nitrophenylamine, 5-(4-Methyl-1-piperazinyl)-2-nitroaniline, 1-{3-amino-4-nitrophenyl}-4-methylpiperazine, Oprea1_384504, SCHEMBL77148, benzenamine, 5-(4-methyl-1-piperazinyl)-2-nitro-, MLS000561761, MWLBMGPQZJDFKZ-UHFFFAOYSA-N, HMS2526H24, ALBB-024876, CS-M3609, BDBM50544037, CL1614, SBB014001, STK057070, AKOS000423586, AC-3594, BP-10025, SMR000174167, ST006459, SY007570, DB-006916, EN300-719622, AB00074319-01, AG-690/33045044, 12R-0229, Z57205499

Application

5-(4-Methylpiperazin-1-yl)-2-nitroaniline is primarily used as a key intermediate in the synthesis of pharmacologically active compounds, particularly in the development of antipsychotic and anticancer agents. Its nitroaniline structure allows for further functionalization via reduction or coupling reactions. Researchers also employ it in the study of piperazine-based ligand-receptor interactions. This compound is valuable in dye and pigment research due to its aromatic nitro group.

Safety and Hazards

GHS Hazard Statements

• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (50%)
• Acute Tox. 4 (50%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• Acute Tox. 4 (50%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.