Description

4,4′-Thiobis(2-tert-butyl-6-methylphenol) (CAS No. 96-66-2) is a high-performance phenolic antioxidant widely used in polymer stabilization and industrial applications. With the molecular formula C₂₂H₃₀O₂S, this compound features a sulfur-bridged bisphenol structure, offering excellent thermal and oxidative stability. Its IUPAC name, 2-tert-butyl-4-(3-tert-butyl-4-hydroxy-5-methylphenyl)sulfanyl-6-methylphenol, reflects its sterically hindered phenolic groups, which effectively scavenge free radicals to prevent degradation. This antioxidant is particularly effective in polyolefins, elastomers, and lubricants, enhancing product lifespan under harsh conditions. Available in powder or granular form, it is compatible with a wide range of processing methods. Store in a cool, dry place away from direct sunlight to maintain efficacy.

Properties

• CAS Number: 96-66-2
• Complexity: 396
• IUPAC Name: 2-tert-butyl-4-(3-tert-butyl-4-hydroxy-5-methyl-phenyl)sulfanyl-6-methyl-phenol
• InChI: InChI=1S/C22H30O2S/c1-13-9-15(11-17(19(13)23)21(3,4)5)25-16-10-14(2)20(24)18(12-16)22(6,7)8/h9-12,23-24H,1-8H3
• InChI Key: YFHKLSPMRRWLKI-UHFFFAOYSA-N
• Exact Mass: 358.19665137
• Molecular Formula: C22H30O2S
• Molecular Weight: 358.5
• SMILES: CC1=CC(=CC(=C1O)C(C)(C)C)SC2=CC(=C(C(=C2)C)O)C(C)(C)C
• Topological: 65.8
• Monoisotopic Mass: 358.19665137
• Physical Description: Off-white crystalline powder with a mild phenolic odor;
• Synonyms: 96-66-2, Antioxidant E 736, Tioalkofen BM, Antioxidant 736, Ethyl 736, Ethyl antioxidant 736, Ethanox 736, 4,4′-Thiobis(2-tert-butyl-6-methylphenol), 6,6′-Di-tert-butyl-4,4′-thiodi-o-cresol, Phenol, 4,4′-thiobis[2-(1,1-dimethylethyl)-6-methyl-, NSC 58409, E 736, 4,4′-Thio-bis(6-tert-butyl-o-cresol), 9NZP7NUO2Y, EINECS 202-522-6, o-CRESOL, 4,4′-THIOBIS(6-t-BUTYL-, BRN 2061707, Phenol, 4,4′-thiobis(2-(1,1-dimethylethyl)-6-methyl-, NSC-58409, o-Cresol, 4,4′-thiobis(6-tert-butyl-, o-Cresol, 4,4′-thiobis[6-tert-butyl-, 4,4′-Thiobis(2-(1,1-dimethylethyl)-6-methylphenol), DTXSID8059136, E-736, 4,4′-Thiobis[2-tert-butyl-6-methylphenol], Lowinox TBO6, oCresol, 4,4’thiobis(6tbutyl, 4,4’Thiobis(6tertbutylocresol), DTXCID9048986, oCresol, 4,4’thiobis(6tertbutyl, 6,6’Ditertbutyl4,4’thiodiocresol, 4,4’Thiobis(2methyl6tertbutylphenol), oCresol, 4,4’thiobis(6tertbutyl (8CI), o-Cresol, 4,4′-thiobis(6-tert-butyl-(8CI), 4,4’Thiobis(2(1,1dimethylethyl)6methylphenol), Phenol, 4,4’thiobis(2(1,1dimethylethyl)6methyl, 202-522-6, 4,4′-Thiobis(6-tert-butyl-o-cresol), Thioalkofen BM, 4,4′-Thiobis(2-(tert-butyl)-6-methylphenol), TB 2, 4,4′-sulfanediylbis(2-tert-butyl-6-methylphenol), 2-tert-butyl-4-(3-tert-butyl-4-hydroxy-5-methylphenyl)sulfanyl-6-methylphenol, MFCD00008823, 3-tert-Butyl-4-hydroxy-5-methylphenyl sulfide, NSC58409, 2-tert-butyl-4-[(3-tert-butyl-4-hydroxy-5-methylphenyl)sulfanyl]-6-methylphenol, 3-t-butyl-4-hydroxy-5-methylphenyl sulfide, 4,4/’-Thiobis(2-tert-butyl-o-methylphenol), 2-(tert-butyl)-4-[3-(tert-butyl)-4-hydroxy-5-methylphenylthio]-6-methylphenol, 4,4′-Thiobis(2-methyl-6-tert-butylphenol), UNII-9NZP7NUO2Y, NCIOpen2_007803, Oprea1_507371, Oprea1_649972, SCHEMBL27236, YFHKLSPMRRWLKI-UHFFFAOYSA-, o-Cresol,4′-thiobis(6-t-butyl-, 4,4′-thiobis(6-t-butyl-o-cresol), o-Cresol,4′-thiobis[6-tert-butyl-, AKOS001017065, 2-tert-butyl-4-(3-tert-butyl-4-hydroxy-5-methyl-phenyl)sulfanyl-6-methyl-phenol, 4,4′-Thiobis(6-tert-butyl-o-cresol), NCGC00334036-01, ST033361, SY051764, 3-t-butyl-4-hydroxy-5-methylphenylsulfide, CS-0179768, NS00040497, T1672, 3-tert-butyl-4-hydroxy-5methylphenyl sulfide, D92499, AB00375978-03, bis(3-t-butyl-4-hydroxy-5-methylphenyl) sulfide, 4,4′-THIOBIS(2-METHYL-6-T-BUTYL) PHENOL, Bis(3-tert-butyl-4-hydroxy-5-methylphenyl) Sulfide, Phenol,4′-thiobis[2-(1,1-dimethylethyl)-6-methyl-, Q27272800, WLN: 1X1&1&R BQ C1 ESR DQ C1 DX1&1&1, Z56791647, 4,4 inverted exclamation mark -Thiobis[2-(tert-butyl)-6-methylphenol], InChI=1/C22H30O2S/c1-13-9-15(11-17(19(13)23)21(3,4)5)25-16-10-14(2)20(24)18(12-16)22(6,7)8/h9-12,23-24H,1-8H3

Application

4,4′-Thiobis(2-tert-butyl-6-methylphenol) is primarily used as a stabilizer in polymers such as polyethylene and polypropylene to prevent oxidative degradation during processing and end-use. It also finds application in rubber and adhesive formulations, where it extends service life by inhibiting chain scission and crosslinking. Additionally, this antioxidant is employed in lubricants and fuels to minimize sludge formation and viscosity changes under high-temperature conditions.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.4%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.