Description
4-(Trimethylsilyl)pyridine (CAS No. 18301-46-7) is a high-purity organosilicon compound with the molecular formula C8H13NSi. This specialized reagent, also known as trimethyl(pyridin-4-yl)silane, is widely utilized in organic synthesis, catalysis, and material science applications. The compound features a pyridine ring substituted with a trimethylsilyl group at the 4-position, offering unique reactivity as both a nucleophile and a silylating agent. Our product is rigorously tested to ensure exceptional quality, with typical purity levels ≥98% (GC). Supplied in moisture-resistant packaging under inert atmosphere to maintain stability, this chemical is ideal for demanding synthetic protocols. Available in quantities from grams to kilograms to meet both research and production-scale needs.
Properties
- CAS Number: 18301-46-7
- Complexity: 100
- IUPAC Name: trimethyl(4-pyridyl)silane
- InChI: InChI=1S/C8H13NSi/c1-10(2,3)8-4-6-9-7-5-8/h4-7H,1-3H3
- InChI Key: PYUVWRKNVLSJJE-UHFFFAOYSA-N
- Exact Mass: 151.081725953
- Molecular Formula: C8H13NSi
- Molecular Weight: 151.28
- SMILES: C[Si](C)(C)C1=CC=NC=C1
- Topological: 12.9
- Monoisotopic Mass: 151.081725953
- Synonyms: 4-(TRIMETHYLSILYL)PYRIDINE, 18301-46-7, trimethyl(pyridin-4-yl)silane, Pyridine, 4-(trimethylsilyl)-, 4-trimethylsilylpyridine, Pyridine,4-(trimethylsilyl)-, MFCD11520474, 4-Trimethylsilanyl-pyridine, SCHEMBL1460348, DTXSID10171376, PYUVWRKNVLSJJE-UHFFFAOYSA-N, AKOS006326015, DB-367110
Application
4-(Trimethylsilyl)pyridine serves as a versatile building block in pharmaceutical intermediates and as a ligand in transition metal catalysis. The compound is particularly valuable in nucleophilic aromatic substitution reactions where the trimethylsilyl group acts as a temporary protecting group or directing moiety. Researchers employ this reagent in the synthesis of silicon-containing heterocycles and as a precursor for advanced materials with tailored electronic properties. Its stability and reactivity make it suitable for both solution-phase and surface modification applications.
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