Description

Description

4-Nitrophenylsulfur Pentafluoride (CAS No. 2613-27-6) is a highly specialized fluorinated organosulfur compound with the molecular formula C₆H₄F₅NO₂S. This chemical, also known by its IUPAC name pentafluoro-(4-nitrophenyl)-??⁶-sulfane, is a valuable reagent in advanced synthetic chemistry and materials science. Its unique structure features a pentafluorosulfur (SF₅) group attached to a nitrophenyl ring, making it an excellent candidate for electrophilic fluorination reactions and as a building block for high-performance materials.

Our product is synthesized under strict quality control to ensure high purity (>98%) and consistency, making it ideal for research applications requiring precise reactivity. It is supplied as a crystalline solid with careful handling instructions due to its moisture sensitivity. Each batch undergoes rigorous analytical characterization including ¹H NMR, ¹⁹F NMR, and LC-MS to verify identity and purity.

Packaged in amber glass vials under inert atmosphere to ensure stability, this compound is particularly useful for:

• Development of SF₅-containing pharmaceuticals
• Advanced material synthesis
• Electrophilic fluorination reactions
• Click chemistry applications

Application

4-Nitrophenylsulfur Pentafluoride serves as a versatile reagent in medicinal chemistry for introducing SF₅ groups into bioactive molecules, enhancing their metabolic stability and lipophilicity. In materials science, it’s used to synthesize high-performance polymers with exceptional thermal and chemical resistance. The compound’s strong electrophilic character makes it valuable for developing new fluorination methodologies in organic synthesis.

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