Description

4-Nitro-N-methylphthalimide (CAS No. 41663-84-7) is a high-purity nitro-substituted phthalimide derivative with the molecular formula C₉H₆N₂O₄. This compound, also known by its IUPAC name 2-methyl-5-nitroisoindole-1,3-dione, is a versatile building block in organic synthesis and pharmaceutical research. Its crystalline structure and well-defined reactivity make it ideal for nucleophilic substitution reactions, cyclizations, and as a precursor for heterocyclic compounds. With a molecular weight of 206.16 g/mol, it exhibits excellent stability under standard laboratory conditions. Our product is rigorously tested for purity (typically ≥97% by HPLC) and is supplied in amber glass vials to ensure long-term integrity. Researchers value this compound for its electron-withdrawing nitro group, which enhances its utility in the synthesis of dyes, agrochemicals, and bioactive molecules.

Properties

• CAS Number: 41663-84-7
• Complexity: 335
• IUPAC Name: 2-methyl-5-nitro-isoindoline-1,3-dione
• InChI: InChI=1S/C9H6N2O4/c1-10-8(12)6-3-2-5(11(14)15)4-7(6)9(10)13/h2-4H,1H3
• InChI Key: JBCHWGTZAAZJKG-UHFFFAOYSA-N
• Exact Mass: 206.03275668
• Molecular Formula: C9H6N2O4
• Molecular Weight: 206.15
• SMILES: CN1C(=O)C2=C(C1=O)C=C(C=C2)[N+](=O)[O-]
• Topological: 83.2
• Monoisotopic Mass: 206.03275668
• Physical Description: Water or Solvent Wet Solid; Dry Powder
• Synonyms: 41663-84-7, N-Methyl-4-nitrophthalimide, 4-Nitro-N-methylphthalimide, 1H-Isoindole-1,3(2H)-dione, 2-methyl-5-nitro-, 2-methyl-5-nitro-1H-isoindole-1,3(2H)-dione, EINECS 255-483-2, 6A6EF017ZM, DTXSID7028013, Phthalimide, N-methyl-4-nitro-, AI3-28673, DTXCID308013, NITRO-N-METHYLPHTHALIMIDE, 4-, 255-483-2, 2-methyl-5-nitroisoindoline-1,3-dione, 2-methyl-5-nitroisoindole-1,3-dione, METHYLNITROPHTHALIMIDE, 2-methyl-5-nitrobenzo[c]azoline-1,3-dione, 2-Methyl-5-nitro-isoindole-1,3-dione, UNII-6A6EF017ZM, MFCD00454263, Oprea1_571303, 4-nitro-N-methyl phthalimide, SCHEMBL516995, SCHEMBL1704508, CHEMBL2022011, JBCHWGTZAAZJKG-UHFFFAOYSA-, Tox21_200196, BBL002082, STK391582, AKOS000668464, CCG-233390, CS-W015337, SB64030, NCGC00248558-01, NCGC00257750-01, AS-15819, ST009484, CAS-41663-84-7, M1310, NS00031031, EN300-06016, D70559, Q27264407, Z53838030, 2-methyl-5-nitro-2,3-dihydro-1H-isoindole-1,3-dione, F1414-0777, InChI=1/C9H6N2O4/c1-10-8(12)6-3-2-5(11(14)15)4-7(6)9(10)13/h2-4H,1H3

Application

4-Nitro-N-methylphthalimide serves as a key intermediate in the synthesis of specialty chemicals, particularly in the development of pharmaceuticals and agrochemicals. Its nitro group facilitates electrophilic aromatic substitution reactions, making it valuable for constructing complex heterocycles. In material science, it contributes to the development of high-performance polymers and dyes due to its rigid aromatic backbone. Researchers also utilize it as a photoactive probe in mechanistic studies of organic transformations.

Safety and Hazards

GHS Hazard Statements

• H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P316, P305+P351+P338, P321, P330, P337+P317, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (100%)
• Eye Irrit. 2 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.