Description

4-Methoxypyridine (CAS No. 620-08-6) is a high-purity organic compound with the molecular formula C₆H₇NO. This versatile heterocyclic aromatic compound features a methoxy group (-OCH₃) at the 4-position of the pyridine ring, enhancing its reactivity as an electron-rich intermediate in synthetic chemistry. Ideal for pharmaceutical, agrochemical, and material science research, our 4-Methoxypyridine is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed, light-resistant packaging to maintain stability. Suitable for use as a ligand, catalyst modifier, or building block in cross-coupling reactions, nucleophilic substitutions, and other fine chemical syntheses. Available in quantities ranging from grams to kilograms to meet both lab-scale and industrial demands.

Properties

• CAS Number: 620-08-6
• Complexity: 59.5
• IUPAC Name: 4-methoxypyridine
• InChI: InChI=1S/C6H7NO/c1-8-6-2-4-7-5-3-6/h2-5H,1H3
• InChI Key: XQABVLBGNWBWIV-UHFFFAOYSA-N
• Exact Mass: 109.052763847
• Molecular Formula: C6H7NO
• Molecular Weight: 109.13
• SMILES: COC1=CC=NC=C1
• Topological: 22.1
• Monoisotopic Mass: 109.052763847
• Synonyms: 4-Methoxypyridine, 620-08-6, Pyridine, 4-methoxy-, .gamma.-Methoxypyridine, EINECS 210-624-7, DTXSID10211029, gamma-Methoxypyridine, DTXCID60133520, 210-624-7, inchi=1/c6h7no/c1-8-6-2-4-7-5-3-6/h2-5h,1h, xqabvlbgnwbwiv-uhfffaoysa-n, 4-methoxy-pyridine, MFCD00674049, gamma-Methoxypyridine;, p-methoxypyridine, methyl pyridin-4-yl ether, 4-methoxypyrdine, 4-methoxylpyridine, 4-methoxy pyridine, 4-Methoxypyridine 95+%, 4-Methoxypyridine, 97%, SCHEMBL61314, SCHEMBL61315, SCHEMBL294190, SCHEMBL349250, SCHEMBL1978251, SCHEMBL3614113, SCHEMBL3617189, SCHEMBL10297348, BCP26365, AKOS002664334, AC-7005, CS-W007634, HY-W007634, PS-9280, SY003216, DB-006867, M1696, NS00022519, EN300-84486, AC-907/25004551

Application

4-Methoxypyridine serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the modification of active pharmaceutical ingredients (APIs) to enhance bioavailability. It is widely employed as a ligand in transition metal-catalyzed reactions, such as palladium-catalyzed cross-couplings, due to its electron-donating properties. Researchers also utilize it in agrochemical development and as a precursor for advanced materials, including liquid crystals and conductive polymers.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (96.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.