Description

4-Hydroxybenzeneacetamide (CAS: 17194-82-0) is a high-purity organic compound with the molecular formula C₈H₉NO₂. This white to off-white crystalline powder is a key intermediate in pharmaceutical synthesis and biochemical research. With a melting point of approximately 168-172°C, it offers excellent stability for various applications. Our product is meticulously synthesized to achieve ≥99% purity (HPLC) and undergoes rigorous QC testing including NMR, MS, and HPLC analysis to ensure batch-to-batch consistency. Suitable for use as a reference standard, this compound is packaged under inert atmosphere in amber glass vials with secure closures to maintain integrity. Special handling is recommended – store at 2-8°C in a dry environment. Available in research quantities from 100mg to 10kg scale, with custom synthesis options available. This product is for research use only, not for drug, household, or other uses.

Properties

• CAS Number: 17194-82-0
• Complexity: 139
• IUPAC Name: 2-(4-hydroxyphenyl)acetamide
• InChI: InChI=1S/C8H9NO2/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4,10H,5H2,(H2,9,11)
• InChI Key: YBPAYPRLUDCSEY-UHFFFAOYSA-N
• Exact Mass: 151.063328530
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.16
• SMILES: C1=CC(=CC=C1CC(=O)N)O
• Topological: 63.3
• Monoisotopic Mass: 151.063328530
• Synonyms: 4-Hydroxyphenylacetamide, 17194-82-0, 2-(4-Hydroxyphenyl)acetamide, 4-Hydroxybenzeneacetamide, p-Hydroxyphenylacetamide, Benzeneacetamide, 4-hydroxy-, p-(Carbamoylmethyl)phenol, (p-Hydroxyphenyl)acetamide, 2-(p-Hydroxyphenyl)acetamide, (4-Hydroxyphenyl)acetamide, 4-(Hydroxyphenyl)acetamide, Acetamide, 2-(p-hydroxyphenyl)-, EINECS 241-235-0, 0HY0N4ITN4, BRN 2085984, NSC-187193, DTXSID4066171, YBPAYPRLUDCSEY-UHFFFAOYSA-, HYDROXYPHENYLACETAMIDE, 4-, 3-10-00-00434 (Beilstein Handbook Reference), NSC 187193, DTXCID6035497, 241-235-0, inchi=1/c8h9no2/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4,10h,5h2,(h2,9,11), MFCD00017145, CHEMBL447310, 4-hydroxy phenylacetamide, UNII-0HY0N4ITN4, 2-(4-Hydroxyphenyl)-ethylamide, 2-(4-Hydroxyphenyl)acetamide; Atenolol Imp. A (EP); Atenolol Impurity A, P-Hydroxyphenyl-acetamide, P-HYDROXY BENZYLAMIDE, Oprea1_206241, SCHEMBL661973, 4-Hydroxyphenylacetamide, 99%, SCHEMBL1302222, SCHEMBL4044552, SCHEMBL4147484, SCHEMBL6632816, alpha-(p-Hydroxyphenyl)acetamide, CHEBI:194828, BBL012281, BDBM50339587, NSC187193, SBB028300, STL163593, AKOS005716492, AC-6787, CCG-356424, CS-W016314, FH37650, PS-4609, s12297, ST088608, SY001683, DB-043877, H0853, NS00025637, EN300-219225, Q27236794

4-Hydroxybenzeneacetamide serves as a crucial building block in pharmaceutical synthesis, particularly in beta-blocker production. Researchers utilize this compound as a precursor in cardiovascular drug development and as a standard in analytical chemistry. Its phenolic hydroxyl group makes it valuable for conjugation chemistry in proteomics studies. The compound also finds use in material science as a monomer for specialty polymers. Always handle using appropriate PPE and follow laboratory safety protocols.

Safety and Hazards

GHS Hazard Statements

• H315 (94.2%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (94.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (92.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (94.2%)
• Eye Irrit. 2 (94.2%)
• STOT SE 3 (92.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.