Description

4-Hydroxy-o-toluic acid (CAS No. 578-39-2), also known as 4-hydroxy-2-methylbenzoic acid, is a high-purity organic compound with the molecular formula C₈H₈O₃. This white to off-white crystalline powder is a valuable intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. With a molecular weight of 152.15 g/mol, it features both a carboxylic acid and a hydroxyl group on a methyl-substituted benzene ring, offering versatile reactivity for derivatization. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied with full analytical documentation including NMR, HPLC, and MS spectra. Ideal for research in medicinal chemistry, this compound is packaged under inert gas to ensure stability and shipped with temperature control as needed.

Properties

• CAS Number: 578-39-2
• Complexity: 155
• IUPAC Name: 4-hydroxy-2-methyl-benzoic acid
• InChI: InChI=1S/C8H8O3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3,(H,10,11)
• InChI Key: BBMFSGOFUHEVNP-UHFFFAOYSA-N
• Exact Mass: 152.047344113
• Molecular Formula: C8H8O3
• Molecular Weight: 152.15
• SMILES: CC1=C(C=CC(=C1)O)C(=O)O
• Topological: 57.5
• Monoisotopic Mass: 152.047344113
• Synonyms: 4-hydroxy-2-methylbenzoic acid, 578-39-2, 4-Hydroxy-o-toluic acid, 4,2-Cresotic acid, Benzoic acid, 4-hydroxy-2-methyl-, 2-methyl-4-hydroxybenzoic acid, U4NMG5AH8R, EINECS 209-422-1, NSC 85496, NSC-85496, DTXSID10206490, 4-hydroxy-2-methylbenzoate, DTXCID10128981, 209-422-1, MFCD02182261, 4-hydroxy-2-methylbenzoicacid, 4-hydroxy-2-methyl-benzoic acid, NSC85496, UNII-U4NMG5AH8R, methyl p-hydroxybenzoic acid, SCHEMBL39526, CHEMBL4250257, para-hydroxy-methyl-benzoic acid, 4-Hydroxy-2-methyl benzoic acid, BBMFSGOFUHEVNP-UHFFFAOYSA-N, CHEBI:167791, BCP24571, SBB064774, AKOS005256094, 4-Hydroxy-2-methylbenzoic acid, 98%, AC-7750, CS-W016305, FS-3561, SY014356, H1311, NS00014690, EN300-117016, AL-398/25017049, Z1255361025

Application

4-Hydroxy-o-toluic acid serves as a key building block in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other pharmacologically active compounds. Researchers utilize this compound in developing novel benzoic acid derivatives for antimicrobial and antioxidant applications. In material science, it acts as a precursor for liquid crystal polymers and specialty coatings requiring hydroxyl-functionalized aromatic cores.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H318 (98.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H335 (23.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P354+P338, P317, P319, P330, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Eye Dam. 1 (98.2%)
• STOT SE 3 (23.6%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.