Atomfair

Awaiting product image

Atomfair 4-Fluorophenyl trifluoromethanesulfonate 4-Fluorophenyltriflate C7H4F4O3S

Description 4-Fluorophenyl trifluoromethanesulfonate (CAS No. 132993-23-8) is a high-purity fluorinated organic sulfonate ester with the molecular formula C7H4F4O3S . This compound, also known as 4-Fluorophenyltriflate , is a versatile reagent widely used in organic synthesis, particularly in the introduction of the trifluoromethanesulfonate (triflate) group. Its IUPAC name is (4-fluorophenyl) trifluoromethanesulfonate , and it is characterized by its high reactivity as an electrophile in cross-coupling reactions, such as Suzuki, Stille, and Negishi couplings. This product is supplied as a clear to pale yellow liquid, stored under inert conditions to ensure stability. It is highly reactive with nucleophiles and must be handled…

Category:
Brands:

Description

Description

4-Fluorophenyl trifluoromethanesulfonate (CAS No. 132993-23-8) is a high-purity fluorinated organic sulfonate ester with the molecular formula C7H4F4O3S. This compound, also known as 4-Fluorophenyltriflate, is a versatile reagent widely used in organic synthesis, particularly in the introduction of the trifluoromethanesulfonate (triflate) group. Its IUPAC name is (4-fluorophenyl) trifluoromethanesulfonate, and it is characterized by its high reactivity as an electrophile in cross-coupling reactions, such as Suzuki, Stille, and Negishi couplings.

This product is supplied as a clear to pale yellow liquid, stored under inert conditions to ensure stability. It is highly reactive with nucleophiles and must be handled with care under anhydrous conditions. Ideal for researchers and chemists working in pharmaceutical, agrochemical, and materials science applications, this compound is a critical building block for the synthesis of complex fluorinated molecules.

Key synonyms include: 4-Fluorophenyl triflate, (4-fluorophenyl) trifluoromethanesulfonate, and 4-Fluorophenyl trifluoromethanesulphonate.

  • CAS No: 132993-23-8
  • Molecular Formula: C7H4F4O3S
  • Molecular Weight: 244.17
  • Exact Mass: 243.98172781
  • Monoisotopic Mass: 243.98172781
  • IUPAC Name: (4-fluorophenyl) trifluoromethanesulfonate
  • SMILES: C1=CC(=CC=C1OS(=O)(=O)C(F)(F)F)F
  • Synonyms: 4-Fluorophenyl trifluoromethanesulfonate, 132993-23-8, 4-Fluorophenyltriflate, (4-fluorophenyl) trifluoromethanesulfonate, 4-Fluorophenyl trifluoromethanesulphonate

Application

4-Fluorophenyl trifluoromethanesulfonate is a key reagent in organic synthesis, particularly for introducing triflate groups in aromatic systems. It is widely used in palladium-catalyzed cross-coupling reactions to form carbon-carbon and carbon-heteroatom bonds. This compound is also valuable in the preparation of fluorinated pharmaceuticals and agrochemicals due to its ability to act as a leaving group in nucleophilic substitution reactions. Its reactivity makes it suitable for constructing complex molecular architectures in medicinal chemistry and materials science.

If you are interested or have any questions, please contact us at support@atomfair.com