Description

Description

4-Fluorobenzoic Acid (CAS No. 1194-02-1) is a high-purity fluorinated aromatic carboxylic acid with the molecular formula C₇H₅FO₂. This white to off-white crystalline powder is widely used in pharmaceutical, agrochemical, and material science research due to its versatile reactivity as a building block. With a melting point of 182-185??C and molecular weight of 140.11 g/mol, it offers excellent stability for synthetic applications. Our product is rigorously tested to ensure ??98% purity (HPLC) and is available in various packaging options to suit laboratory-scale or bulk requirements. The compound’s para-fluorine substitution enhances its electron-withdrawing properties, making it particularly valuable for nucleophilic aromatic substitution reactions and metal-catalyzed cross-coupling processes.

Key Features:

• IUPAC Name: 4-fluorobenzoic acid
• Synonyms: p-Fluorobenzoic acid, Benzoic acid, 4-fluoro-
• High chemical purity for sensitive applications
• Moisture-sensitive: store in cool, dry conditions
• Compatible with common organic solvents including ethanol, DMSO, and dichloromethane

Application

4-Fluorobenzoic acid serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly COX-2 inhibitors and antifungal agents. Its carboxyl group enables easy derivatization to esters, amides, and acid chlorides for drug discovery applications. The compound is also employed in liquid crystal material synthesis and as a standard in fluorine NMR spectroscopy. Researchers utilize its unique electronic properties to study substituent effects in aromatic systems and to develop novel PET radiotracers.

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