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Atomfair 4′-Fluoroacetophenone p-Fluoroacetophenone C8H7FO

Description 4′-Fluoroacetophenone (CAS No. 403-42-9) is a high-purity fluorinated aromatic ketone with the molecular formula C8H7FO . This compound, also known by its IUPAC name 1-(4-fluorophenyl)ethanone , is a versatile building block in organic synthesis and pharmaceutical research. It features a fluorine substituent at the para position of the acetophenone ring, enhancing its reactivity in electrophilic and nucleophilic reactions. Ideal for use in Suzuki couplings, Grignard reactions, and as a precursor for fluorinated intermediates, this product is rigorously tested for purity (typically ??98% by GC) and consistency. Available in scalable quantities, it is supplied in secure, chemically resistant packaging to…

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Description

Description

4′-Fluoroacetophenone (CAS No. 403-42-9) is a high-purity fluorinated aromatic ketone with the molecular formula C8H7FO. This compound, also known by its IUPAC name 1-(4-fluorophenyl)ethanone, is a versatile building block in organic synthesis and pharmaceutical research. It features a fluorine substituent at the para position of the acetophenone ring, enhancing its reactivity in electrophilic and nucleophilic reactions. Ideal for use in Suzuki couplings, Grignard reactions, and as a precursor for fluorinated intermediates, this product is rigorously tested for purity (typically ??98% by GC) and consistency. Available in scalable quantities, it is supplied in secure, chemically resistant packaging to ensure stability and shelf life. Suitable for researchers in medicinal chemistry, material science, and fine chemical synthesis.

  • CAS No: 403-42-9
  • Molecular Formula: C8H7FO
  • Molecular Weight: 138.14
  • Exact Mass: 138.048093005
  • Monoisotopic Mass: 138.048093005
  • IUPAC Name: 1-(4-fluorophenyl)ethanone
  • SMILES: CC(=O)C1=CC=C(C=C1)F
  • Synonyms: 4′-Fluoroacetophenone, 1-(4-Fluorophenyl)ethanone, 4-FLUOROACETOPHENONE, p-Fluoroacetophenone, 1-(4-Fluorophenyl)Ethan-1-One

Application

4′-Fluoroacetophenone is widely used as a key intermediate in the synthesis of fluorinated pharmaceuticals, agrochemicals, and liquid crystal materials. Its para-fluorine substitution makes it valuable for designing bioactive molecules with enhanced metabolic stability and binding affinity. Researchers employ it in cross-coupling reactions to construct complex aryl-fluorine scaffolds. Additionally, it serves as a precursor for photoinitiators and specialty polymers requiring fluorinated aromatic components.

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