Description

4-Fluoro-3-nitrobenzotrifluoride (CAS No. 367-86-2) is a high-purity fluorinated aromatic compound with the molecular formula C₇H₃F₄NO₂. Also known as 1-fluoro-2-nitro-4-(trifluoromethyl)benzene, this specialty chemical is widely used in pharmaceutical, agrochemical, and materials science research. Its unique structure, featuring both nitro and trifluoromethyl functional groups, makes it a valuable intermediate for synthesizing complex molecules. Our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed, light-resistant containers to maintain stability. Suitable for use in Suzuki couplings, nucleophilic substitutions, and other fine chemical transformations.

Properties

• CAS Number: 367-86-2
• Complexity: 225
• IUPAC Name: 1-fluoro-2-nitro-4-(trifluoromethyl)benzene
• InChI: InChI=1S/C7H3F4NO2/c8-5-2-1-4(7(9,10)11)3-6(5)12(13)14/h1-3H
• InChI Key: HLDFCCHSOZWKAA-UHFFFAOYSA-N
• Exact Mass: 209.00999099
• Molecular Formula: C7H3F4NO2
• Molecular Weight: 209.10
• SMILES: C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])F
• Topological: 45.8
• Monoisotopic Mass: 209.00999099
• Synonyms: 4-Fluoro-3-nitrobenzotrifluoride, 367-86-2, 1-Fluoro-2-nitro-4-(trifluoromethyl)benzene, Benzene, 1-fluoro-2-nitro-4-(trifluoromethyl)-, 3-Nitro-alpha,alpha,alpha,4-tetrafluorotoluene, SFN4U7RYL9, 3-Nitro-4-fluoro benzotrifluoride, NSC-10303, 2-fluoro-5-trifluoromethyl nitrobenzene, 1-Fluoro-2-nitro-4-trifluoromethyl-benzene, 4-fluoro-3-nitrotrifluoromethylbenzene, 3-nitro-4-fluorobenzotrifluoride, 3-nitro-4-fluorotrifluorotoluol, NSC10303, EINECS 206-702-5, MFCD00007059, UNII-SFN4U7RYL9, SCHEMBL5961, DTXSID5073169, SCHEMBL13076923, 4-fluoro-3-nitro-benzotrifluoride, 4-fluoro-3-nitrobenzo trifluoride, NIKYUPOKNFUXPQ-UHFFFAOYSA-N, 4-fluoro-3-nitro-benzo trifluoride, NSC 10303, SBB009902, STL453754, 2-fluoro-5-trifluorometyl nitrobenzene, AKOS000120901, AC-2520, CS-W015173, 2-nitro-4-trifluoromethylfluoro-benzene, 4-Fluoro-3-nitrobenzotrifluoride, 96%, 4-Fluoro-3-nitrobenzotrifluoride, 99%, ST060486, 1-fluoro-2-nitro-4-trifluoromethylbenzene, 1-Fluoro-4-trifluoromethyl-2-nitrobenzene, A6331, F0324, NS00041715, EN300-18690, 1-Fluoro-2-nitro-4-(trifluoromethyl)benzene #, alpha,alpha,alpha,4-Tetrafluoro-3-nitrotoluene, D70871, 3-nitro-I+/-,I+/-,I+/-,4-tetrafluorotoluene, 4-Fluoro-3-nitrobenzotrifluoride, technical grade, Z87002576, 3-Nitro-4-Fluorobenzotrifluoride; 1-Fluoro-2-nitro-4-(trifluoromethyl)-benzene, InChI=1/C7H3F4NO2/c8-5-2-1-4(7(9,10)11)3-6(5)12(13)14/h1-3

Application

4-Fluoro-3-nitrobenzotrifluoride serves as a key building block in medicinal chemistry for developing fluorinated drug candidates. The compound’s electron-withdrawing groups facilitate electrophilic aromatic substitution reactions in agrochemical synthesis. Researchers also utilize it as a precursor for liquid crystals and specialty polymers requiring thermal/chemical resistance.

Safety and Hazards

GHS Hazard Statements

• H226 (87.8%): Flammable liquid and vapor [Warning Flammable liquids]
• H302 (12.2%): Harmful if swallowed [Warning Acute toxicity, oral]
• H311 (10.2%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (10.2%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (85.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (87.8%)
• Skin Irrit. 2 (98%)
• Eye Irrit. 2 (98%)
• STOT SE 3 (85.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.