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Atomfair 4-Fluoro-3-formyl-5-methylphenylboronic acid C8H8BFO3
Description 4-Fluoro-3-formyl-5-methylphenylboronic acid (CAS No. 1310384-23-6) is a high-purity boronic acid derivative with the molecular formula C8H8BFO3. This compound features a reactive boronic acid group (-B(OH)2) adjacent to a formyl (-CHO) and a fluoro (-F) substituent on a methyl-substituted aromatic ring, making it a versatile building block for Suzuki-Miyaura cross-coupling reactions and other organoboron-mediated transformations. Its IUPAC name is (4-fluoro-3-formyl-5-methylphenyl)boronic acid , and it is supplied as a white to off-white crystalline powder with ??95% purity (HPLC). Ideal for pharmaceutical, agrochemical, and materials science research, this reagent is packaged under inert conditions to ensure stability. Store at 2-8??C in a…
Description
Description
4-Fluoro-3-formyl-5-methylphenylboronic acid (CAS No. 1310384-23-6) is a high-purity boronic acid derivative with the molecular formula C8H8BFO3. This compound features a reactive boronic acid group (-B(OH)2) adjacent to a formyl (-CHO) and a fluoro (-F) substituent on a methyl-substituted aromatic ring, making it a versatile building block for Suzuki-Miyaura cross-coupling reactions and other organoboron-mediated transformations. Its IUPAC name is (4-fluoro-3-formyl-5-methylphenyl)boronic acid, and it is supplied as a white to off-white crystalline powder with ??95% purity (HPLC). Ideal for pharmaceutical, agrochemical, and materials science research, this reagent is packaged under inert conditions to ensure stability. Store at 2-8??C in a dry environment. Synonyms include MFCD11111909 and Boronic acid, B-(4-fluoro-3-formyl-5-methylphenyl)-.
- CAS No: 1310384-23-6
- Molecular Formula: C8H8BFO3
- Molecular Weight: 181.96
- Exact Mass: 182.0550524
- Monoisotopic Mass: 182.0550524
- IUPAC Name: (4-fluoro-3-formyl-5-methylphenyl)boronic acid
- SMILES: B(C1=CC(=C(C(=C1)C=O)F)C)(O)O
- Synonyms: 1310384-23-6, 4-FLUORO-3-FORMYL-5-METHYLPHENYLBORONIC ACID, (4-Fluoro-3-formyl-5-methylphenyl)boronic acid, Boronic acid, B-(4-fluoro-3-formyl-5-methylphenyl)-, MFCD11111909
Application
4-Fluoro-3-formyl-5-methylphenylboronic acid is widely used as a key intermediate in palladium-catalyzed cross-coupling reactions to synthesize biaryl compounds for drug discovery. Its formyl group enables further functionalization via condensation or reduction, while the fluorine atom enhances metabolic stability in bioactive molecules. Researchers employ it in the development of fluorescent probes and polymeric materials due to its unique electronic properties. Suitable for high-throughput screening in medicinal chemistry.
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