Description

4-Chloro-3-(trifluoromethyl)benzaldehyde (CAS No. 34328-46-6) is a high-purity aromatic aldehyde featuring a chloro and trifluoromethyl substituent on the benzene ring. With the molecular formula C₈H₄ClF₃O, this compound is a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique electronic and steric properties make it ideal for nucleophilic addition reactions, condensation reactions, and as a precursor for heterocyclic compounds. This product is rigorously tested for quality, ensuring ≥98% purity (GC), and is supplied in sealed containers to maintain stability. Suitable for research and industrial applications, it is handled under controlled conditions to ensure safety and performance consistency.

Properties

• CAS Number: 34328-46-6
• Complexity: 192
• IUPAC Name: 4-chloro-3-(trifluoromethyl)benzaldehyde
• InChI: InChI=1S/C8H4ClF3O/c9-7-2-1-5(4-13)3-6(7)8(10,11)12/h1-4H
• InChI Key: NIHMMULLFBKTOK-UHFFFAOYSA-N
• Exact Mass: 207.9902769
• Molecular Formula: C8H4ClF3O
• Molecular Weight: 208.56
• SMILES: C1=CC(=C(C=C1C=O)C(F)(F)F)Cl
• Topological: 17.1
• Monoisotopic Mass: 207.9902769
• Synonyms: 4-Chloro-3-(trifluoromethyl)benzaldehyde, 34328-46-6, EINECS 251-940-5, DTXSID50187895, DTXCID10110386, 251-940-5, 4-chloro-3-trifluoromethylbenzaldehyde, MFCD00040722, 4-chloro-3-trifluoromethyl-benzaldehyde, 4-Chloro-3-(trifluoromethyl)benzaldehyde, 97%, Benzaldehyde, 4-chloro-3-(trifluoromethyl)-, 4-chloro-3trifluoromethyl-benzaldehyde, SCHEMBL40676, SCHEMBL2520644, SCHEMBL27974318, BBL103877, CL8344, SBB003468, STL557687, AKOS005257785, CS-W008104, DS-1376, PS-8032, 3-trifluoromethyl-4-chloro-benzaldehyde, AC-27962, SY020691, 4-chloranyl-3-(trifluoromethyl)benzaldehyde, C2760, NS00059649, ST50825573, EN300-67007, A822830, F0001-1000, Z1065866152

Application

4-Chloro-3-(trifluoromethyl)benzaldehyde is widely used as a key intermediate in the synthesis of bioactive molecules, including pharmaceutical candidates and agrochemicals. Its reactive aldehyde group facilitates the construction of complex structures via condensation or cyclization reactions. Researchers utilize this compound in the development of fluorinated compounds, leveraging the trifluoromethyl group’s metabolic stability and lipophilicity. It is also employed in material science for designing advanced polymers and coatings.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.8%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.