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Atomfair 4-Chloro-3-(trifluoromethyl)aniline C7H5ClF3N

Description 4-Chloro-3-(trifluoromethyl)aniline (CAS No. 320-51-4) is a high-purity aromatic amine derivative with the molecular formula C7H5ClF3N . This compound features a chloro-substituted benzene ring with a trifluoromethyl group and an amino group at the meta and para positions, respectively, making it a versatile intermediate in organic synthesis and pharmaceutical applications. Its unique structural properties enable reactivity in electrophilic substitution and cross-coupling reactions. Available in >98% purity (HPLC), it is supplied as a crystalline solid with strict quality control to ensure consistency for research and industrial use. Ideal for use in Suzuki-Miyaura couplings, amidation reactions, and as a precursor for agrochemicals…

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Description

Description

4-Chloro-3-(trifluoromethyl)aniline (CAS No. 320-51-4) is a high-purity aromatic amine derivative with the molecular formula C7H5ClF3N. This compound features a chloro-substituted benzene ring with a trifluoromethyl group and an amino group at the meta and para positions, respectively, making it a versatile intermediate in organic synthesis and pharmaceutical applications. Its unique structural properties enable reactivity in electrophilic substitution and cross-coupling reactions. Available in >98% purity (HPLC), it is supplied as a crystalline solid with strict quality control to ensure consistency for research and industrial use. Ideal for use in Suzuki-Miyaura couplings, amidation reactions, and as a precursor for agrochemicals and pharmaceuticals. Store under inert conditions at 2-8??C to maintain stability.

  • CAS No: 320-51-4
  • Molecular Formula: C7H5ClF3N
  • Molecular Weight: 195.57
  • Exact Mass: 195.0062613
  • Monoisotopic Mass: 195.0062613
  • IUPAC Name: 4-chloro-3-(trifluoromethyl)aniline
  • SMILES: C1=CC(=C(C=C1N)C(F)(F)F)Cl
  • Synonyms: 4-Chloro-3-(trifluoromethyl)aniline, 5-Amino-2-chlorobenzotrifluoride, 2-Chloro-5-aminobenzotrifluoride, Benzenamine, 4-chloro-3-(trifluoromethyl)-, 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine

Application

4-Chloro-3-(trifluoromethyl)aniline is widely employed as a key intermediate in the synthesis of pharmaceuticals, particularly for bioactive molecules targeting CNS disorders and antimicrobial agents. Its trifluoromethyl group enhances lipophilicity, making it valuable in agrochemical development for herbicides and fungicides. Researchers also utilize it in material science for constructing fluorinated polymers with enhanced thermal and chemical resistance.

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