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Atomfair 4-Chloro-1-fluoro-2-nitrobenzene C6H3ClFNO2

Description 4-Chloro-1-fluoro-2-nitrobenzene (CAS No. 345-18-6) is a high-purity aromatic compound with the molecular formula C6H3ClFNO2, widely utilized in organic synthesis and pharmaceutical research. This yellow crystalline solid exhibits excellent stability under standard conditions, making it a reliable reagent for nucleophilic substitution reactions, cross-coupling methodologies, and heterocyclic scaffold construction. Its unique halogen-nitro substitution pattern enables selective functionalization, particularly in the synthesis of agrochemicals, dyes, and advanced intermediates. Packaged under inert gas to ensure longevity, our product undergoes rigorous QC testing (HPLC, GC, NMR) to guarantee ??98% purity. Available in scalable quantities from grams to multi-kilogram batches, it is supplied with comprehensive…

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Description

Description

4-Chloro-1-fluoro-2-nitrobenzene (CAS No. 345-18-6) is a high-purity aromatic compound with the molecular formula C6H3ClFNO2, widely utilized in organic synthesis and pharmaceutical research. This yellow crystalline solid exhibits excellent stability under standard conditions, making it a reliable reagent for nucleophilic substitution reactions, cross-coupling methodologies, and heterocyclic scaffold construction. Its unique halogen-nitro substitution pattern enables selective functionalization, particularly in the synthesis of agrochemicals, dyes, and advanced intermediates. Packaged under inert gas to ensure longevity, our product undergoes rigorous QC testing (HPLC, GC, NMR) to guarantee ??98% purity. Available in scalable quantities from grams to multi-kilogram batches, it is supplied with comprehensive analytical documentation (CoA, MSDS) to support regulatory compliance.

  • CAS No: 345-18-6
  • Molecular Formula: C6H3ClFNO2
  • Molecular Weight: 175.54
  • Exact Mass: 174.9836342
  • Monoisotopic Mass: 174.9836342
  • IUPAC Name: 4-chloro-1-fluoro-2-nitrobenzene
  • SMILES: C1=CC(=C(C=C1Cl)[N+](=O)[O-])F
  • Synonyms: 5-chloro-2-fluoronitrobenzene, 4-Chloro-1-fluoro-2-nitrobenzene, 2-fluoro-5-chloronitrobenzene, Benzene, 4-chloro-1-fluoro-2-nitro-, MAM88XP8XP

Application

4-Chloro-1-fluoro-2-nitrobenzene serves as a key precursor in Suzuki-Miyaura and Buchwald-Hartwig couplings for pharmaceutical building blocks. Its electron-deficient aromatic ring facilitates nucleophilic aromatic substitution (SNAr) reactions to create fluorinated aniline derivatives. Researchers employ this compound in the development of herbicides, liquid crystal materials, and PET radiotracer synthesis due to its balanced reactivity profile.

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