Description

4-Bromophthalic anhydride (CAS: 86-90-8) is a high-purity brominated aromatic anhydride with the molecular formula C₈H₃BrO₃. This white to off-white crystalline powder is widely used as a key intermediate in organic synthesis, particularly in the production of dyes, pigments, and specialty polymers. Its reactive anhydride group and bromine substituent make it a versatile building block for pharmaceuticals, agrochemicals, and advanced materials. With a melting point of 130-134°C and a molecular weight of 227.01 g/mol, this compound is soluble in common organic solvents like DMSO and acetone but insoluble in water. Packaged under inert conditions to ensure stability, our 4-Bromophthalic anhydride is rigorously tested for purity (≥98% by HPLC) and is ideal for research, industrial applications, and fine chemical synthesis.

Properties

• CAS Number: 86-90-8
• Complexity: 238
• IUPAC Name: 5-bromoisobenzofuran-1,3-dione
• InChI: InChI=1S/C8H3BrO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H
• InChI Key: BCKVHOUUJMYIAN-UHFFFAOYSA-N
• Exact Mass: 225.92656
• Molecular Formula: C8H3BrO3
• Molecular Weight: 227.01
• SMILES: C1=CC2=C(C=C1Br)C(=O)OC2=O
• Topological: 43.4
• Monoisotopic Mass: 225.92656
• Synonyms: 4-Bromophthalic anhydride, 86-90-8, 5-bromoisobenzofuran-1,3-dione, 4-Bromo Phthalic anhydride, 2D7E8SD3ZF, 5-BROMO-ISOBENZOFURAN-1,3-DIONE, EINECS 201-707-9, DTXSID70235342, DTXCID70157833, 201-707-9, 5-Bromo-2-benzofuran-1,3-dione, 5-bromo-1,3-dihydro-2-benzofuran-1,3-dione, 1,3-Isobenzofurandione, 5-bromo-, 4-Bromophthalicanhydride, MFCD00191323, 4-Bromo-phthalic anhydride, 4-BROMOPHTHALIC ACID ANHYDRIDE, 5-bromophthalic anhydride, UNII-2D7E8SD3ZF, SCHEMBL135902, SBB008534, 5-Bromo-2-benzofuran-1,3-dione #, AKOS000121183, AC-7938, CS-W019549, FS-1200, PB33839, 5-BROMO-1,3-ISOBENZOFURANDIONE, SY014696, DB-002561, B1693, NS00020453, EN300-18058, P16601

4-Bromophthalic anhydride serves as a critical precursor in the synthesis of brominated phthalocyanine dyes used in photodynamic therapy and optoelectronic devices. It is also employed in the preparation of flame-retardant additives for polymers due to its bromine content. Researchers utilize this compound to develop novel pharmaceutical intermediates and liquid crystal materials. Its reactivity allows for facile functionalization in cross-coupling reactions, making it valuable in medicinal chemistry.

Safety and Hazards

GHS Hazard Statements

• H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (33.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H318 (16.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (83.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H334 (16.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
• H335 (66.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (33.3%)
• Skin Irrit. 2 (66.7%)
• Skin Sens. 1 (33.3%)
• Eye Dam. 1 (16.7%)
• Eye Irrit. 2 (83.3%)
• Resp. Sens. 1 (16.7%)
• STOT SE 3 (66.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.