Atomfair 4-Bromophenyl trifluoromethanesulfonate 4-Bromophenyl triflate, 4-Bromophenyltriflate C7H4BrF3O3S

Description 4-Bromophenyl trifluoromethanesulfonate (CAS No. 129112-25-0) is a high-purity, organobromine sulfonate compound with the molecular formula C7H4BrF3O3S . This reagent is widely utilized in organic synthesis, particularly as a versatile electrophile in cross-coupling reactions and as a precursor for aryl functionalization. Its triflate (-OSO2CF3) group serves as an excellent leaving group, enabling efficient nucleophilic substitution reactions under mild conditions. The bromine substituent at the para position further enhances its reactivity in metal-catalyzed transformations such as Suzuki, Heck, and Stille couplings. Supplied as a crystalline solid or solution, our product undergoes rigorous QC testing (HPLC, NMR) to ensure ??98% purity, making…

Description

4-Bromophenyl trifluoromethanesulfonate (CAS No. 129112-25-0) is a high-purity, organobromine sulfonate compound with the molecular formula C₇H₄BrF₃O₃S. This reagent is widely utilized in organic synthesis, particularly as a versatile electrophile in cross-coupling reactions and as a precursor for aryl functionalization. Its triflate (-OSO₂CF₃) group serves as an excellent leaving group, enabling efficient nucleophilic substitution reactions under mild conditions. The bromine substituent at the para position further enhances its reactivity in metal-catalyzed transformations such as Suzuki, Heck, and Stille couplings. Supplied as a crystalline solid or solution, our product undergoes rigorous QC testing (HPLC, NMR) to ensure ??98% purity, making it ideal for pharmaceutical, agrochemical, and materials science research. Store under inert atmosphere at 2-8??C to maintain stability.

CAS No: 129112-25-0
Molecular Formula: C7H4BrF3O3S
Molecular Weight: 305.07
Exact Mass: 303.90166
Monoisotopic Mass: 303.90166
IUPAC Name: (4-bromophenyl) trifluoromethanesulfonate
SMILES: C1=CC(=CC=C1OS(=O)(=O)C(F)(F)F)Br
Synonyms: 4-Bromophenyl trifluoromethanesulfonate, 66107-30-0, 4-Bromophenyltriflate, 4-Bromophenyl triflate, (4-bromophenyl) trifluoromethanesulfonate

Application

4-Bromophenyl trifluoromethanesulfonate is extensively employed as a key intermediate in palladium-catalyzed cross-coupling reactions for biaryl synthesis. It serves as an electrophilic partner in Suzuki-Miyaura couplings to construct complex aromatic systems for drug discovery. The compound’s triflate group facilitates efficient substitution in nucleophilic aromatic reactions, while the bromo substituent allows sequential functionalization. Researchers also utilize it to prepare liquid crystals and OLED materials via selective aryl-aryl bond formation.

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