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Atomfair 4-Bromo-3-(trifluoromethyl)benzoic acid C8H4BrF3O2

Description 4-Bromo-3-(trifluoromethyl)benzoic acid (CAS No. 161622-14-6) is a high-purity aromatic carboxylic acid derivative with the molecular formula C8H4BrF3O2. This compound features a bromo substituent at the 4-position and a trifluoromethyl group at the 3-position of the benzoic acid scaffold, making it a versatile building block for organic synthesis, pharmaceuticals, and agrochemical applications. Its unique electronic and steric properties enhance reactivity in cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Suitable for researchers and industrial chemists, this product is rigorously tested for purity (typically ??97% by HPLC or GC) and is available in various packaging options to meet laboratory-scale or bulk requirements.…

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Description

Description

4-Bromo-3-(trifluoromethyl)benzoic acid (CAS No. 161622-14-6) is a high-purity aromatic carboxylic acid derivative with the molecular formula C8H4BrF3O2. This compound features a bromo substituent at the 4-position and a trifluoromethyl group at the 3-position of the benzoic acid scaffold, making it a versatile building block for organic synthesis, pharmaceuticals, and agrochemical applications. Its unique electronic and steric properties enhance reactivity in cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Suitable for researchers and industrial chemists, this product is rigorously tested for purity (typically ??97% by HPLC or GC) and is available in various packaging options to meet laboratory-scale or bulk requirements. Store in a cool, dry place under inert conditions to ensure stability.

  • CAS No: 161622-14-6
  • Molecular Formula: C8H4BrF3O2
  • Molecular Weight: 269.01
  • Exact Mass: 267.93468
  • Monoisotopic Mass: 267.93468
  • IUPAC Name: 4-bromo-3-(trifluoromethyl)benzoic acid
  • SMILES: C1=CC(=C(C=C1C(=O)O)C(F)(F)F)Br
  • Synonyms: 4-Bromo-3-(trifluoromethyl)benzoic acid, 161622-14-6, 630-304-4, 1622-14-6, 4-Bromo-3-trifluoromethylbenzoic acid

Application

4-Bromo-3-(trifluoromethyl)benzoic acid is widely used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) with trifluoromethyl motifs. It serves as a precursor for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to construct biaryl systems. The compound is also employed in agrochemical research for designing herbicides and fungicides due to its bioactivity-enhancing trifluoromethyl group. Additionally, it finds utility in material science for creating specialty polymers and ligands for catalysis.

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