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Atomfair 4-Bromo-3-(trifluoromethyl)aniline C7H5BrF3N

Description 4-Bromo-3-(trifluoromethyl)aniline (CAS No. 393-36-2) is a high-purity aromatic amine derivative with the molecular formula C7H5BrF3N . This compound features a bromo-substituted aniline core with a trifluoromethyl group at the 3-position, making it a versatile building block for pharmaceutical, agrochemical, and materials science applications. Its unique electronic and steric properties enable selective functionalization in cross-coupling reactions, nucleophilic substitutions, and other synthetic transformations. Supplied as a crystalline solid with ??98% purity (HPLC), it is rigorously tested for consistency, stability, and low heavy metal content. Ideal for researchers developing fluorinated bioactive molecules or advanced materials. Store under inert atmosphere at 2-8??C to…

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Description

Description

4-Bromo-3-(trifluoromethyl)aniline (CAS No. 393-36-2) is a high-purity aromatic amine derivative with the molecular formula C7H5BrF3N. This compound features a bromo-substituted aniline core with a trifluoromethyl group at the 3-position, making it a versatile building block for pharmaceutical, agrochemical, and materials science applications. Its unique electronic and steric properties enable selective functionalization in cross-coupling reactions, nucleophilic substitutions, and other synthetic transformations. Supplied as a crystalline solid with ??98% purity (HPLC), it is rigorously tested for consistency, stability, and low heavy metal content. Ideal for researchers developing fluorinated bioactive molecules or advanced materials. Store under inert atmosphere at 2-8??C to maintain optimal stability.

  • CAS No: 393-36-2
  • Molecular Formula: C7H5BrF3N
  • Molecular Weight: 240.02
  • Exact Mass: 238.95575
  • Monoisotopic Mass: 238.95575
  • IUPAC Name: 4-bromo-3-(trifluoromethyl)aniline
  • SMILES: C1=CC(=C(C=C1N)C(F)(F)F)Br
  • Synonyms: 4-Bromo-3-(trifluoromethyl)aniline, 393-36-2, 5-Amino-2-bromobenzotrifluoride, 4-bromo-3-trifluoromethylaniline, 4-Bromo-3-trifluoromethyl-phenylamine

Application

4-Bromo-3-(trifluoromethyl)aniline serves as a key intermediate in Suzuki-Miyaura and Buchwald-Hartwig couplings for pharmaceutical candidates targeting CNS disorders. The trifluoromethyl group enhances metabolic stability in agrochemicals like herbicides and insecticides. Its electron-deficient aromatic system facilitates electrophilic substitutions in dye and polymer synthesis. Researchers also exploit its halogenated structure for PET radioligand development.

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