Description

4-Bromo-3-hydroxybenzoic acid (CAS No. 14348-38-0) is a high-purity brominated hydroxybenzoic acid derivative with the molecular formula C₇H₅BrO₃. This compound is a versatile aromatic carboxylic acid featuring both a bromo and a hydroxyl substituent on the benzene ring, making it a valuable intermediate in organic synthesis and pharmaceutical research. With a molecular weight of 217.02 g/mol, it exhibits excellent reactivity for electrophilic substitution and coupling reactions. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a fine white to off-white crystalline powder. Ideal for use in Suzuki-Miyaura cross-coupling, esterification, and as a precursor for bioactive molecule development. Packaged under inert gas to ensure stability and shipped with comprehensive analytical data (MSDS, ¹H/¹³C NMR, FTIR).

Properties

• CAS Number: 14348-38-0
• Complexity: 160
• IUPAC Name: 4-bromo-3-hydroxy-benzoic acid
• InChI: InChI=1S/C7H5BrO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,(H,10,11)
• InChI Key: PAJSESFUWIYFNF-UHFFFAOYSA-N
• Exact Mass: 215.94221
• Molecular Formula: C7H5BrO3
• Molecular Weight: 217.02
• SMILES: C1=CC(=C(C=C1C(=O)O)O)Br
• Topological: 57.5
• Monoisotopic Mass: 215.94221
• Synonyms: 4-Bromo-3-hydroxybenzoic acid, 14348-38-0, Benzoic acid, 4-bromo-3-hydroxy-, DTXSID20423595, DTXCID80374433, 630-184-3, pajsesfuwiyfnf-uhfffaoysa-n, 4-bromo-3-hydroxy benzoic acid, MFCD08056371, 4-bromo-3-hydroxybenzoicacid, p-Brom-m-oxybenzoesaure, SCHEMBL1812684, 4-Bromo-3-hydroxy-benzoic acid, BBL101377, s5444, STL555173, AKOS005258209, CCG-266697, CS-W003445, FS-2435, HY-W003445, PD088077, SY012255, DB-011302, EN300-109810, Z1269234103

Application

4-Bromo-3-hydroxybenzoic acid serves as a key building block in medicinal chemistry for the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs) and antimicrobial agents. Its reactive bromo and carboxyl groups enable efficient derivatization for creating complex heterocycles in agrochemical and pharmaceutical R&D. The compound is also employed in material science as a monomer for functionalized polymers and liquid crystals. Researchers utilize it as a probe in studying enzyme inhibition mechanisms due to its structural resemblance to natural phenolic acids.

Safety and Hazards

GHS Hazard Statements

• H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (33.3%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (33.3%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (66.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (66.7%)
• Eye Irrit. 2A (66.7%)
• STOT SE 3 (66.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.