Description

Description

(4-Bromo-3-fluorophenyl)methanamine hydrochloride (CAS No. 1214342-53-6) is a high-purity organic compound with the molecular formula C₇H₈BrClFN, widely used in pharmaceutical and chemical research. This hydrochloride salt features a bromo- and fluoro-substituted phenyl ring, making it a valuable intermediate in the synthesis of bioactive molecules, including drug candidates and agrochemicals. Its IUPAC name is (4-bromo-3-fluorophenyl)methanamine;hydrochloride, and it is supplied as a white to off-white crystalline powder with guaranteed ??95% purity (HPLC). Suitable for use in cross-coupling reactions, amidation, and other functional group transformations, this compound is rigorously tested for quality, stability, and consistency. Packaged under inert conditions to ensure long-term stability, it is ideal for researchers requiring reliable building blocks for medicinal chemistry and material science applications.

Application

(4-Bromo-3-fluorophenyl)methanamine hydrochloride serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and CNS-targeting drugs. Its halogenated aromatic structure enables participation in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. Researchers also utilize it in the preparation of fluorinated analogs for SAR studies in drug discovery. The compound’s amine functionality allows for further derivatization into amides, sulfonamides, or ureas.

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