Description

4-Bromo-3-chlorobenzaldehyde (CAS No. 120077-69-2) is a high-purity halogenated benzaldehyde derivative with the molecular formula C₇H₄BrClO. This aromatic aldehyde is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and material science research. Its unique structure, featuring both bromo and chloro substituents on the benzene ring, enables selective functionalization for cross-coupling reactions, nucleophilic substitutions, and condensation reactions. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC) and is supplied in sealed amber vials under inert atmosphere to prevent degradation. Ideal for Suzuki-Miyaura couplings, Grignard reactions, and as a precursor for heterocyclic compounds. Available in quantities from 1g to 1kg with optional COA and NMR spectra upon request.

Properties

• CAS Number: 120077-69-2
• Complexity: 129
• IUPAC Name: 4-bromo-3-chloro-benzaldehyde
• InChI: InChI=1S/C7H4BrClO/c8-6-2-1-5(4-10)3-7(6)9/h1-4H
• InChI Key: LDYVDYZLCRUOTM-UHFFFAOYSA-N
• Exact Mass: 217.91341
• Molecular Formula: C7H4BrClO
• Molecular Weight: 219.46
• SMILES: C1=CC(=C(C=C1C=O)Cl)Br
• Topological: 17.1
• Monoisotopic Mass: 217.91341
• Synonyms: 4-Bromo-3-chlorobenzaldehyde, 120077-69-2, DTXSID60555081, DTXCID60505864, 816-998-3, 4-Bromo-3-chloro-benzaldehyde, Benzaldehyde, 4-bromo-3-chloro-, MFCD08059110, 3-chloro4-bromo-benzaldehyde, 3-chloro-4-bromo-benzaldehyde, SCHEMBL1572335, Benzaldehyde,4-bromo-3-chloro-, LDYVDYZLCRUOTM-UHFFFAOYSA-N, BCP14717, AKOS015835300, AB43050, CS-W005655, AS-18814, SY014683, EN300-111461, Z1269162864

Application

4-Bromo-3-chlorobenzaldehyde serves as a key intermediate in the synthesis of bioactive molecules, including kinase inhibitors and antimicrobial agents. Its aldehyde group facilitates Schiff base formation for ligand design in coordination chemistry. The compound is also employed in material science for constructing liquid crystals and OLED precursors. Researchers utilize its halogenated aromatic core for palladium-catalyzed cross-coupling reactions in medicinal chemistry workflows.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (66.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (66.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.