Atomfair 4-Bromo-2-methoxypyridine C6H6BrNO CAS 100367-39-3

4-Bromo-2-methoxypyridine (CAS: 100367-39-3) is a high-purity brominated pyridine derivative with the molecular formula C6H6BrNO . This compound is an essential building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring a bromine atom at the 4-position and a methoxy group at the 2-position of the pyridine ring, makes it a versatile intermediate for cross-coupling reactions such as Suzuki, Stille, and Buchwald-Hartwig couplings. Ideal for researchers and scientists, our product is rigorously tested for purity (>98%) and consistency, ensuring reliable performance in complex synthetic pathways. Available in various quantities, from milligrams to kilograms, to meet both…

Description

4-Bromo-2-methoxypyridine (CAS: 100367-39-3) is a high-purity brominated pyridine derivative with the molecular formula C6H6BrNO. This compound is an essential building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring a bromine atom at the 4-position and a methoxy group at the 2-position of the pyridine ring, makes it a versatile intermediate for cross-coupling reactions such as Suzuki, Stille, and Buchwald-Hartwig couplings. Ideal for researchers and scientists, our product is rigorously tested for purity (>98%) and consistency, ensuring reliable performance in complex synthetic pathways. Available in various quantities, from milligrams to kilograms, to meet both lab-scale and industrial needs.

Properties

  • CAS Number: 100367-39-3
  • Complexity: 89.1
  • IUPAC Name: 4-bromo-2-methoxy-pyridine
  • InChI: InChI=1S/C6H6BrNO/c1-9-6-4-5(7)2-3-8-6/h2-4H,1H3
  • InChI Key: YFTGMMXMLPTTAY-UHFFFAOYSA-N
  • Exact Mass: 186.96328
  • Molecular Formula: C6H6BrNO
  • Molecular Weight: 188.02
  • SMILES: COC1=NC=CC(=C1)Br
  • Topological: 22.1
  • Monoisotopic Mass: 186.96328
  • Synonyms: 4-Bromo-2-methoxypyridine, 100367-39-3, DTXSID80555220, DTXCID10506003, 640-169-3, Pyridine, 4-bromo-2-methoxy-, MFCD08277268, 4-bromanyl-2-methoxy-pyridine, 4-bromo-2-methoxy-pyridine, 2-methoxy-4-bromopyridine, SCHEMBL132442, WLZ3025, YFTGMMXMLPTTAY-UHFFFAOYSA-N, CS-D0772, BBL101240, SBB054328, STL555036, AKOS005257660, AB44876, AC-7007, PS-3477, SY008980, EN300-87235, IJO

4-Bromo-2-methoxypyridine is widely used as a key intermediate in the synthesis of pharmaceuticals, including kinase inhibitors and antiviral agents. It serves as a precursor in palladium-catalyzed cross-coupling reactions to construct complex heterocyclic frameworks. Researchers also employ it in material science for developing functionalized pyridine-based ligands and catalysts. Its stability and reactivity make it suitable for high-throughput screening and combinatorial chemistry applications.

Safety and Hazards

GHS Hazard Statements

  • H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (16.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (16.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (33.3%)
  • Acute Tox. 4 (16.7%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • Acute Tox. 4 (16.7%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.