Description

Description

4-Bromo-1,1,1-trifluorobutane (CAS No. 406-81-5) is a high-purity halogenated organic compound with the molecular formula C₄H₆BrF₃. This colorless to pale yellow liquid is characterized by its trifluoromethyl group and bromine substitution, making it a versatile intermediate in synthetic organic chemistry and materials science. With a molecular weight of 178.99 g/mol, it is commonly employed in nucleophilic substitution reactions, fluorination processes, and as a building block for pharmaceuticals, agrochemicals, and specialty polymers. Our product is rigorously tested for purity (typically ??97% by GC) and is supplied in sealed, light-resistant containers to ensure stability. Ideal for researchers in organofluorine chemistry, this compound offers excellent reactivity for C-C bond formation and functional group transformations under controlled conditions.

Application

4-Bromo-1,1,1-trifluorobutane serves as a key precursor in the synthesis of fluorinated pharmaceuticals and liquid crystal materials. Its reactive bromine terminus enables cross-coupling reactions (e.g., Suzuki, Heck) to introduce trifluorobutyl motifs into target molecules. The compound is also utilized in polymer chemistry to modify surface properties and create hydrophobic coatings. Researchers value its utility in developing PET radiotracers due to the favorable pharmacokinetics imparted by the trifluoromethyl group.

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