Description

4-Bromo-1-chloro-2-(4-ethoxy-benzyl)-benzene (CAS No. 461432-23-5) is a high-purity halogenated aromatic compound with the molecular formula C₁₅H₁₄BrClO. This specialized chemical is designed for advanced research and industrial applications, offering exceptional stability and reactivity for synthetic organic chemistry. Its unique structure, featuring bromo and chloro substituents on the benzene ring alongside an ethoxybenzyl group, makes it a valuable intermediate in pharmaceuticals, agrochemicals, and material science. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC), with detailed analytical data (NMR, MS) available upon request. Packaged under inert gas to prevent degradation, it is supplied in amber glass vials or bulk quantities with customizable options.

Properties

• CAS Number: 461432-23-5
• Complexity: 241
• IUPAC Name: 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
• InChI: InChI=1S/C15H14BrClO/c1-2-18-14-6-3-11(4-7-14)9-12-10-13(16)5-8-15(12)17/h3-8,10H,2,9H2,1H3
• InChI Key: ZUNCHZBITMUSRD-UHFFFAOYSA-N
• Exact Mass: 323.99166
• Molecular Formula: C15H14BrClO
• Molecular Weight: 325.63
• SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)Br)Cl
• Topological: 9.2
• Monoisotopic Mass: 323.99166
• Synonyms: 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene, 4-bromo-1-chloro-2-(4-ethoxy-benzyl)-benzene, 4-Bromo-1-chloro-2-((4-ethoxyphenyl)methyl)benzene, 636-921-5, 928-048-6, 461432-23-5, 4-bromo-1-chloro-2-(4-ethoxybenzyl)benzene, 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether, 5-Bromo-2-chloro-4′-ethoxydiphenylmethane, Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-, 5-bromo-2-chloro-4 inverted exclamation mark -ethoxydiphenylmethane, MFCD11042292, 2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene, C15H14BrClO, 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene; 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene, SCHEMBL38150, 9BH764JHR9, DTXSID60433931, ZUNCHZBITMUSRD-UHFFFAOYSA-N, BCP08717, CS-B0023, SBB054221, AKOS015917373, FB76075, SB17549, AC-26384, DS-12747, SY025637, (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methane, EN300-6735475, (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methylene, 1-[(5-bromo-2-chlorophenyl)methyl]-4-ethoxybenzene, 4-bromo-1-chloro-2-(4-ethoxyphenyl)methyl-benzene, 4-BROMO-1-CHLORO-2-[(4-ETHOXYPHENYL)METHYL]-BENZENE

Application

4-Bromo-1-chloro-2-(4-ethoxy-benzyl)-benzene serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical development for drug candidates targeting CNS disorders. Its halogenated structure enables efficient cross-coupling reactions (e.g., Suzuki-Miyaura) for constructing biaryl systems. Researchers also utilize it in material science to develop liquid crystals and OLED precursors. The ethoxybenzyl moiety enhances solubility in organic solvents, facilitating reaction optimization.

Safety and Hazards

GHS Hazard Statements

• H302 (14.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (12.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H318 (81.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H332 (12.5%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H400 (81.2%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410 (81.2%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P321, P330, P362+P364, P391, and P501

Hazard Classes and Categories

• Acute Tox. 4 (14.6%)
• Acute Tox. 4 (12.5%)
• Eye Dam. 1 (81.2%)
• Acute Tox. 4 (12.5%)
• Aquatic Acute 1 (81.2%)
• Aquatic Chronic 1 (81.2%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.