Description

4-Aminomethylbenzoic Acid (PAMBA) is a high-purity pharmaceutical intermediate and research chemical with the molecular formula C₈H₉NO₂ (CAS: 56-91-7). This white crystalline powder is widely recognized for its role as a hemostatic agent, functioning as a competitive inhibitor of plasminogen activation. With a melting point of ~250°C (dec.) and solubility in water, dilute acids, and alkalis, it is ideal for biochemical and pharmacological applications. Our product is rigorously tested via HPLC (>97% purity) and meets EP/USP standards, ensuring consistency for drug development, clinical research, and analytical reference. Packaged in amber glass vials under inert gas to prevent degradation. Synonyms include Tranexamic Acid Impurity D, 4-Carboxybenzylamine, and Styptopur.

Properties

• CAS Number: 56-91-7
• Complexity: 139
• IUPAC Name: 4-(aminomethyl)benzoic acid
• InChI: InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
• InChI Key: QCTBMLYLENLHLA-UHFFFAOYSA-N
• Exact Mass: 151.063328530
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.16
• SMILES: C1=CC(=CC=C1CN)C(=O)O
• Topological: 63.3
• Monoisotopic Mass: 151.063328530
• Physical Description: Beige powder;
• Vapor Pressure: 0.000264 [mmHg]
• Synonyms: 4-(Aminomethyl)benzoic acid, 56-91-7, 4-Carboxybenzylamine, Aminomethylbenzoic acid, 4-Aminomethylbenzoic acid, Pamba, Styptopur, Gumbix, p-Aminomethylbenzoic acid, Benzoic acid, 4-(aminomethyl)-, Benzylamine-4-carboxylic acid, alpha-Amino-p-toluic acid, p-(Aminomethyl)benzoic acid, 4-Aminomethyl-benzoic acid, 4-(Aminomethyl)benzoesaeure, EINECS 200-297-9, 68WG9JKC7L, NSC 41629, NSC-41629, p-Toluic acid, alpha-amino-, Gumbix (TN), DTXSID20204568, AMINOMETHYLBENZOIC ACID [MART.], AMINOMETHYLBENZOIC ACID [WHO-DD], TRANEXAMIC ACID IMPURITY D [EP IMPURITY], AMINOMETHYLBENZOIC ACID (MART.), para-aminomethylbenzoic acid, TRANEXAMIC ACID IMPURITY D (EP IMPURITY), 4Carboxybenzylamine, alphaAminoptoluic acid, 4aminomethylbenzoic acid, pToluic acid, alphaamino, 4(Aminomethyl)benzoesaeure, p(Aminomethyl)benzoic acid, Benzylamine4carboxylic acid, Benzoic acid, 4(aminomethyl), pToluic acid, alphaamino (8CI), DTXCID50127059, p-Toluic acid, alpha-amino-(8CI), Benzoic acid, 4(aminomethyl) (9CI), Benzoic acid, 4-(aminomethyl)-(9CI), MFCD00010203, NSC41629, tranexamic acid impurity D, .alpha.-Amino-p-toluic acid, 4-(aminomethyl)-benzoic acid, CHEMBL328875, p-Toluic acid, .alpha.-amino-, 4-AMBA, UNII-68WG9JKC7L, 4-(Aminomethyl)benzoicAcid, 4-aminomethylbezoic acid, alphaamino-p-toluic acid, 4-aminomethyl benzoic acid, 4-(aminomethyl)benzoic-acid, NCIStruc1_000124, NCIStruc2_000164, Oprea1_689394, SCHEMBL38758, CBDivE_002627, 4-(aminomethyl) benzoic acid, SCHEMBL679717, GTPL4702, SCHEMBL15666085, SCHEMBL27317060, SCHEMBL27980104, HY-B1258R, CHEBI:134774, BCP24445, HY-B1258, NCI41629, 4-(Aminomethyl)benzoic acid, 97%, 4-(aminomethyl)phenylcarboxylic acid, BDBM50408790, CCG-36812, NCGC00013487, SBB006704, STK246898, AKOS000118982, CS-4892, DB13244, FA10877, 4-(Aminomethyl)benzoic acid (Standard), NCGC00013487-02, NCGC00096601-01, AC-10932, AS-13170, NCI60_003944, SY002868, DB-008385, A0965, NS00001532, ST50165186, EN300-16697, D07568, D70590, AE-562/40225995, Q695442, Aminomethylbenzoic Acid 4-(Aminomethyl)benzoic Acid, F1313-0009, 4AZ

4-Aminomethylbenzoic acid is primarily used as an antifibrinolytic agent to reduce bleeding by inhibiting plasminogen activation. It serves as a key reference standard in QC laboratories for hemostatic drug analysis (e.g., Tranexamic Acid formulations). Researchers also employ it in studying serine protease inhibition mechanisms and developing novel anticoagulant therapies.

Safety and Hazards

GHS Hazard Statements

• H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (95.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (98%)
• Eye Irrit. 2 (98%)
• STOT SE 3 (95.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.