Atomfair 4-Amino-3-fluoropyridine C5H5FN2 CAS 2247-88-3

Description

4-Amino-3-fluoropyridine (CAS No. 2247-88-3) is a high-purity fluorinated pyridine derivative with the molecular formula C₅H₅FN₂. This heterocyclic compound, also known by its IUPAC name 3-fluoropyridin-4-amine, is a valuable building block in pharmaceutical and agrochemical synthesis. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a white to off-white crystalline powder. Suitable for research and industrial applications, it is packaged under inert gas to ensure stability. Storage recommendations: 2-8°C in a tightly sealed container, protected from light and moisture. Available in quantities from 1g to 1kg with custom bulk options.

Properties

• CAS Number: 2247-88-3
• Complexity: 76.8
• IUPAC Name: 3-fluoropyridin-4-amine
• InChI: InChI=1S/C5H5FN2/c6-4-3-8-2-1-5(4)7/h1-3H,(H2,7,8)
• InChI Key: UFIKBUVVVGSMGW-UHFFFAOYSA-N
• Exact Mass: 112.04367633
• Molecular Formula: C5H5FN2
• Molecular Weight: 112.10
• SMILES: C1=CN=CC(=C1N)F
• Topological: 38.9
• Monoisotopic Mass: 112.04367633
• Synonyms: 4-Amino-3-fluoropyridine, 2247-88-3, 4-Pyridinamine, 3-fluoro-, Y744OES4EP, Pyridine, 4-amino-3-fluoro-, UNII-Y744OES4EP, DTXSID70355751, DTXCID80306810, 623-648-1, 3-fluoropyridin-4-amine, MFCD00234072, 3-fluoro-4-aminopyridine, 3-Fluoro-pyridin-4-ylamine, 3-Fluoro-4-pyridinamine, 3-fluoro-4-pyridylamine, 4-amino-3-fluoro-pyridine, SCHEMBL767020, SCHEMBL2067465, SCHEMBL8299615, SCHEMBL29209956, 4-Amino-3-fluoropyridine, 97%, UFIKBUVVVGSMGW-UHFFFAOYSA-N, BCP01703, AC-047, BBL103925, CL0178, SBB069765, STL557735, AKOS005063495, CS-W007902, PB33879, PS-9251, SB10494, SY008130, DB-000379, DB-011288, A2383, EN300-85350

Application

4-Amino-3-fluoropyridine serves as a key intermediate in the synthesis of fluorinated pharmaceutical compounds, particularly kinase inhibitors and CNS-active drugs. The fluorine substitution enhances metabolic stability and bioavailability in drug candidates. Researchers utilize this compound in palladium-catalyzed cross-coupling reactions for constructing complex heterocyclic systems. It’s also employed in material science for developing fluorinated liquid crystals and electronic materials.

Safety and Hazards

GHS Hazard Statements

• H302 (89.1%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (10.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (15.2%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (13%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (89.1%)
• Acute Tox. 4 (10.9%)
• Skin Irrit. 2 (15.2%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (13%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.