Description

4-Amino-2-methylpyridine (CAS: 18437-58-6) is a high-purity organic compound with the molecular formula C₆H₈N₂. This heterocyclic aromatic amine is a valuable intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical research. Our product is rigorously tested to ensure ≥97% purity, making it ideal for precise laboratory applications. The compound appears as a white to off-white crystalline powder with excellent solubility in polar organic solvents. Proper storage under inert conditions ensures long-term stability. Suitable for use in drug discovery, coordination chemistry, and as a ligand or catalyst precursor. Available in research quantities with comprehensive analytical data (GC/MS, NMR, HPLC).

Properties

• CAS Number: 18437-58-6
• Complexity: 72.9
• IUPAC Name: 2-methylpyridin-4-amine
• InChI: InChI=1S/C6H8N2/c1-5-4-6(7)2-3-8-5/h2-4H,1H3,(H2,7,8)
• InChI Key: GNCLPNMQEGMNTG-UHFFFAOYSA-N
• Exact Mass: 108.068748264
• Molecular Formula: C6H8N2
• Molecular Weight: 108.14
• SMILES: CC1=NC=CC(=C1)N
• Topological: 38.9
• Monoisotopic Mass: 108.068748264
• Synonyms: 4-Amino-2-methylpyridine, 18437-58-6, 625-782-6, 4-Amino-2-picoline, 2-methylpyridin-4-amine, 2-methyl-4-aminopyridine, MFCD00186509, 2-Methyl-pyridin-4-ylamine, 2-methyl-4-pyridylamine, 4-pyridinamine, 2-methyl-, 2-methyl-4-pyridinamine, 4-amino-picoline, 4-amino-methylpyridine, 2-methylpyridin-4-amin, NoName_3009, 6-methylpyridin-4-amine, 2-methylpyridine-4-amine, 2-methylpyridin-4-ylamine, 4-amino-2-methyl-pyridine, SCHEMBL266271, SCHEMBL293432, SCHEMBL4823340, SCHEMBL8941078, DTXSID90902504, 4-Amino-2-methylpyridine, 97%, GNCLPNMQEGMNTG-UHFFFAOYSA-N, HMS1716O22, BCP22105, CS-D0974, CL0056, SBB027134, STK695662, AKOS000271091, AC-3013, PS-9288, SB10589, SY003568, DB-009077, ST4148353, A2348, EN300-17881, 4-Amino-2-methylpyridine (4-Amino-2-picoline)

4-Amino-2-methylpyridine serves as a key building block in medicinal chemistry for developing kinase inhibitors and CNS-active compounds. Its pyridine core makes it valuable as a ligand in transition metal catalysis for asymmetric synthesis. The compound also finds use in synthesizing corrosion inhibitors and as a precursor for advanced materials research. Researchers employ it in studying enzyme inhibition mechanisms due to its structural similarity to pyridoxamine.

Safety and Hazards

GHS Hazard Statements

• H302 (97.7%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (93%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (97.7%)
• Skin Irrit. 2 (97.7%)
• Eye Dam. 1 (93%)
• STOT SE 3 (95.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.