Description

(4-(4-Methyl-1,3-thiazol-5-yl)phenyl)methanamine (CAS: 1448189-30-7) is a high-purity synthetic organic compound with the molecular formula C₁₁H₁₂N₂S. This specialized amine derivative features a 4-methyl-1,3-thiazole moiety linked to a benzylamine group, making it a valuable intermediate for pharmaceutical research and medicinal chemistry applications. With a molecular weight of 204.29 g/mol, this compound is supplied as a stable solid with ≥95% purity (HPLC), ensuring consistency for sensitive experimental workflows. Its unique structure enables applications in drug discovery, particularly in kinase inhibitor development and heterocyclic scaffold optimization. Proper storage at 2-8°C under inert conditions is recommended for long-term stability. Available in research quantities (mg to kg scale) with optional analytical certificates (CoA, NMR, MS).

Properties

• CAS Number: 1448189-30-7
• Complexity: 178
• IUPAC Name: [4-(4-methylthiazol-5-yl)phenyl]methanamine
• InChI: InChI=1S/C11H12N2S/c1-8-11(14-7-13-8)10-4-2-9(6-12)3-5-10/h2-5,7H,6,12H2,1H3
• InChI Key: PCZXZPOWHWJXDZ-UHFFFAOYSA-N
• Exact Mass: 204.07211956
• Molecular Formula: C11H12N2S
• Molecular Weight: 204.29
• SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CN
• Topological: 67.2
• Monoisotopic Mass: 204.07211956
• Synonyms: 1448189-30-7, [4-(4-methyl-1,3-thiazol-5-yl)phenyl]methanamine, (4-(4-Methyl-1,3-thiazol-5-yl)phenyl)methanamine, 838-577-3, (4-(4-methylthiazol-5-yl)phenyl)methanamine, 4-(4-Methylthiazol-5-yl)benzylamine, MFCD28965258, 1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methanamine, [4-(4-methylthiazol-5-yl)phenyl]methanamine, 4-(4-Methyl-5-thiazolyl)benzylamine, CHEMBL4906774, SCHEMBL15110380, PCZXZPOWHWJXDZ-UHFFFAOYSA-N, BCP23580, AKOS030235598, AT11306, CS-W021052, 4-(4-Methylthiazol-5-yl)benzylamine HCl, AS-67937, DA-32002, SY216225, EN300-301401, A1-09441

This compound serves as a key building block in medicinal chemistry for the synthesis of kinase inhibitors and targeted therapeutics. Researchers utilize its thiazole-benzylamine scaffold to develop modulators of biological pathways involving protein-protein interactions. It has shown utility in early-stage drug discovery programs focused on oncology and CNS disorders. The structural motif is also employed in fluorescence labeling applications due to its aromatic properties.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.