Description
(3R)-3-Aminotetrahydrofuran hydrochloride (CAS: 1072015-52-1) is a high-purity chiral building block widely used in pharmaceutical research and organic synthesis. With the molecular formula C4H10ClNO, this compound features a tetrahydrofuran ring substituted with an amine group at the (3R) position, making it a valuable intermediate for asymmetric synthesis. The hydrochloride salt ensures stability and solubility for diverse reaction conditions. Ideal for medicinal chemistry, peptide modifications, and catalyst development, this reagent is rigorously tested for quality (≥98% purity) and supplied in sealed packaging to maintain integrity. Suitable for use in GMP-compliant processes and academic research.
Properties
- CAS Number: 1072015-52-1
- Complexity: 46.8
- IUPAC Name: (3R)-tetrahydrofuran-3-amine;hydrochloride
- InChI: InChI=1S/C4H9NO.ClH/c5-4-1-2-6-3-4;/h4H,1-3,5H2;1H/t4-;/m1./s1
- InChI Key: MHOVLDXJDIEEMJ-PGMHMLKASA-N
- Exact Mass: 123.0450916
- Molecular Formula: C4H10ClNO
- Molecular Weight: 123.58
- SMILES: C1COC[C@@H]1N.Cl
- Topological: 35.3
- Monoisotopic Mass: 123.0450916
- Synonyms: 1072015-52-1, (3r)-3-aminotetrahydrofuran hydrochloride, 808-899-9, (R)-tetrahydrofuran-3-amine hydrochloride, (R)-3-aminotetrahydrofuran hydrochloride, (3R)-oxolan-3-amine hydrochloride, (3R)-oxolan-3-amine;hydrochloride, (R)-3-aminotetrahydrofuran HCl, (R)-3-AMINOTETRAHYDROFURAN, HCL, (3R)-Tetrahydro-3-furanamine hydrochloride, MFCD08461720, (R)-Tetrahydro-furan-3-ylamine hydrochloride, SCHEMBL395235, MHOVLDXJDIEEMJ-PGMHMLKASA-N, SC1299, AKOS007930478, CS-W019413, AS-54593, (R)-tetrahydro-furan-3-amine hydrochloride, DB-031087, EN300-256938
This compound serves as a key intermediate in the synthesis of bioactive molecules, particularly in chiral drug development. It is utilized in peptide coupling reactions and as a precursor for heterocyclic scaffolds. Researchers employ it in asymmetric catalysis and ligand design due to its stereochemical purity. Its stability in aqueous and organic phases makes it versatile for combinatorial chemistry.
Safety and Hazards
GHS Hazard Statements
- H318 (90.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
Precautionary Statements
- P264+P265, P280, P305+P354+P338, and P317
Hazard Classes and Categories
- Eye Dam. 1 (90.5%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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