Description

3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS No: 16234-10-9) is a high-purity heterocyclic compound with the molecular formula C₆H₄N₂OS. This thienopyrimidine derivative is a versatile building block in pharmaceutical and agrochemical research, offering a unique scaffold for drug discovery and development. Its fused ring structure enhances binding affinity and metabolic stability, making it valuable for kinase inhibitors and other biologically active molecules. Available in multiple packaging options, our product is rigorously tested for quality (≥98% purity by HPLC) and stability under standard storage conditions. Ideal for medicinal chemistry, combinatorial libraries, and structure-activity relationship (SAR) studies.

Properties

• CAS Number: 16234-10-9
• Complexity: 192
• IUPAC Name: 3H-thieno[3,2-d]pyrimidin-4-one
• InChI: InChI=1S/C6H4N2OS/c9-6-5-4(1-2-10-5)7-3-8-6/h1-3H,(H,7,8,9)
• InChI Key: PZMKGWRBZNOIPQ-UHFFFAOYSA-N
• Exact Mass: 152.00443393
• Molecular Formula: C6H4N2OS
• Molecular Weight: 152.18
• SMILES: C1=CSC2=C1N=CNC2=O
• Topological: 69.7
• Monoisotopic Mass: 152.00443393
• Synonyms: 3H,4H-thieno[3,2-d]pyrimidin-4-one, 3H,4H-thieno(3,2-d)pyrimidin-4-one, 811-135-7, 16234-10-9, Thieno[3,2-d]pyrimidin-4(3H)-one, thieno[3,2-d]pyrimidin-4-ol, 4-Hydroxythieno[3,2-d]pyrimidine, thieno[3,2-d]pyrimidin-4(1h)-one, 1H,4H-Thieno[3,2-d]pyrimidin-4-one, 3H-Thieno[3,2-d]pyrimidin-4-one, 16285-68-0, 1H-thieno[3,2-d]pyrimidin-4-one, CHEMBL1891423, MFCD03407527, MFCD11040452, Thieno[3,2-d]pyrimidine-4(3H)-one, Maybridge1_003845, MLS000760656, SCHEMBL209626, SCHEMBL384424, SCHEMBL384425, SCHEMBL1457910, SCHEMBL6642089, thieno[3,2-d]pyrimidin-4-one, HMS552G17, OSM-S-171, DTXSID20375262, thiopheno[3,2-d]pyrimidin-4-ol, CHEBI:194757, PZMKGWRBZNOIPQ-UHFFFAOYSA-N, 3H-thieno[3,2-d]pyrimid-4-one, HMS2633N20, HMS3363C14, BCP22593, 3H-thieno[3,2-d]pyrimidine-4-one, AB1054, AR2543, BDBM50384077, SBB086859, STK934165, 3H-thieno[3,2-d]-pyrimidin-4-one, 3H-thieno[3,2-d]pyrimid-in-4-one, AKOS001209898, AKOS005073855, AKOS006228164, AC-7413, FS-1501, PB10096, AC-28405, GK 00357, SMR000370597, SY006112, 4-Hydroxythieno[3 pound not2-d]pyrimidine, 1,4-Dihydrothieno[3,2-d]pyrimidin-4-one, DB-005722, DB-026910, CS-0044467, T3301, EN300-23988, 1Z-0222, Z166665672

3H,4H-thieno[3,2-d]pyrimidin-4-one serves as a key intermediate in synthesizing kinase inhibitors and anticancer agents. Its scaffold is utilized in fragment-based drug design (FBDD) due to its hydrogen-bonding capabilities. Researchers employ this compound in high-throughput screening (HTS) for neurodegenerative disease targets. It also finds use in material science as a precursor for organic semiconductors.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.