Description

3,5-Dichloro-2,4,6-trifluoropyridine (CAS No. 1737-93-5) is a highly specialized halogenated pyridine derivative with the molecular formula C₅Cl₂F₃N. This compound features a unique substitution pattern of two chlorine and three fluorine atoms on the pyridine ring, making it a valuable intermediate in organic synthesis and pharmaceutical research. Its high purity and precise structural configuration ensure optimal performance in nucleophilic substitution reactions, cross-coupling reactions, and as a building block for agrochemicals and active pharmaceutical ingredients (APIs). Suitable for use in advanced research and industrial applications, this product is rigorously tested for quality and consistency. Store in a cool, dry place under inert conditions to maintain stability.

Properties

• CAS Number: 1737-93-5
• Complexity: 134
• IUPAC Name: 3,5-dichloro-2,4,6-trifluoro-pyridine
• InChI: InChI=1S/C5Cl2F3N/c6-1-3(8)2(7)5(10)11-4(1)9
• InChI Key: PKSORSNCSXBXOT-UHFFFAOYSA-N
• Exact Mass: 200.9359889
• Molecular Formula: C5Cl2F3N
• Molecular Weight: 201.96
• SMILES: C1(=C(C(=NC(=C1Cl)F)F)Cl)F
• Topological: 12.9
• Monoisotopic Mass: 200.9359889
• Physical Description: 3,5-dichloro-2,4,6-trifluoropyridine appears as a colorless liquid. Insoluble in water and denser than water. Hence sinks in water. Contact may irritate skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
• Synonyms: 3,5-DICHLORO-2,4,6-TRIFLUOROPYRIDINE, 1737-93-5, Pyridine, 3,5-dichloro-2,4,6-trifluoro-, 2,4,6-trifluoro-3,5-dichloropyridine, 3,5-Dichloro-2,4-6-trifluoropyridine, UNII-939242TZ0L, EINECS 217-088-3, 939242TZ0L, DTXSID2042357, DCTFPY, DTXCID0022357, 3,5-DICHLORO-2,4,6-TRI-FLUOROPYRIDINE, pksorsncsxbxot-uhfffaoysa-n, 3,5-Dichlorotrifluoropyridine, MFCD00006226, 2,6-Dichloro-1,3,5-trifluorobenzene, 2,4,6-trifluoro-3,5-dichloro pyridine, NA9264, 3,5-dichloro-2,4,6-trifluoro-pyridine, SCHEMBL282140, CK1209, SBB058355, AKOS005064070, AC-6891, CS-W001247, DB-022014, A3841, D2057, NS00008676, ST50319363, EN300-93763, 3,5-Dichloro-2,4,6-trifluoropyridine, 97%, 3,5-Dichloro-2,4,6-trifluoropyridine, 98%, Q27271577, 3,5-Dichloro-2,4,6-trifluoropyridine [NA9264] [Poison], 3 pound not5-Dichloro-2 pound not4 pound not6-trifluoropyridine

Application

3,5-Dichloro-2,4,6-trifluoropyridine is widely utilized as a key intermediate in the synthesis of fluorinated heterocyclic compounds, particularly in pharmaceutical and agrochemical industries. Its reactive sites enable efficient functionalization, making it ideal for constructing complex molecules such as herbicides, insecticides, and drug candidates. Researchers also employ this compound in material science for developing specialty polymers and coatings with enhanced chemical resistance. Its versatility in nucleophilic aromatic substitution reactions further expands its utility in fine chemical synthesis.

Safety and Hazards

GHS Hazard Statements

• H301 (17.8%): Toxic if swallowed [Danger Acute toxicity, oral]
• H310+H330 (13.6%): Fatal in contact with skin or if inhaled [Danger Acute toxicity, dermal; acute toxicity, inhalation]
• H310 (18.6%): Fatal in contact with skin [Danger Acute toxicity, dermal]
• H315 (99.2%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (13.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H319 (82.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H330 (51.7%): Fatal if inhaled [Danger Acute toxicity, inhalation]
• H335 (84.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H400 (16.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410 (16.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (17.8%)
• Acute Tox. 2 (18.6%)
• Skin Irrit. 2 (99.2%)
• Skin Sens. 1A (13.6%)
• Eye Irrit. 2A (82.2%)
• Acute Tox. 1 (51.7%)
• STOT SE 3 (84.7%)
• Aquatic Acute 1 (16.9%)
• Aquatic Chronic 1 (16.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.