Description

3,5-Dichloro-2-cyanopyridine (CAS No. 85331-33-5) is a high-purity heterocyclic organic compound with the molecular formula C₆H₂Cl₂N₂. This versatile chemical building block features a pyridine core substituted with two chlorine atoms at the 3- and 5-positions and a nitrile group at the 2-position, making it an excellent intermediate for pharmaceutical and agrochemical synthesis. With a molecular weight of 173.00 g/mol, it appears as a white to off-white crystalline powder with exceptional stability under standard conditions. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in sealed containers to maintain integrity. Ideal for nucleophilic substitution reactions, metal-catalyzed cross-couplings, and cyano-group transformations.

Properties

• CAS Number: 85331-33-5
• Complexity: 162
• IUPAC Name: 3,5-dichloropyridine-2-carbonitrile
• InChI: InChI=1S/C6H2Cl2N2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H
• InChI Key: ATUOLSDAAPMVJJ-UHFFFAOYSA-N
• Exact Mass: 171.9595035
• Molecular Formula: C6H2Cl2N2
• Molecular Weight: 173.00
• SMILES: C1=C(C=NC(=C1Cl)C#N)Cl
• Topological: 36.7
• Monoisotopic Mass: 171.9595035
• Synonyms: 85331-33-5, 3,5-Dichloro-2-cyanopyridine, DTXSID90377839, DTXCID50328867, 674-558-4, 3,5-dichloropicolinonitrile, 2-Cyano-3,5-dichloropyridine, 3,5-dichloropyridine-2-carbonitrile, MFCD03788758, 2-Pyridinecarbonitrile, 3,5-dichloro-, SCHEMBL186605, CHEMBL4532928, ATUOLSDAAPMVJJ-UHFFFAOYSA-N, BCP11555, BBL101704, SBB055557, STL555500, 3,5-dichloro-pyridine-2-carbonitrile, AKOS005254208, AC-9467, CS-W003110, DS-0498, FD06012, PS-3447, SB18375, NCGC00664147-01, 3,5-Dichloropyridine-2-carbonitrile, 95%, DB-031926, DB-217803, D4059, ST50408477, EN300-84252, Z1201622473, 2-Cyano-3,5-dichloropyridine;3,5-Dichloropicolinonitrile

Application

3,5-Dichloro-2-cyanopyridine serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and antibacterial agents. Its reactive sites enable efficient functionalization to create complex pyridine derivatives for drug discovery. The compound is also employed in agrochemical research for developing novel pesticides and herbicides. Researchers utilize it in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to construct biaryl systems.

Safety and Hazards

GHS Hazard Statements

• H302 (93.9%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (93.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (93.9%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (95.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (93.9%)
• Acute Tox. 4 (93.9%)
• Skin Irrit. 2 (98%)
• Eye Irrit. 2 (98%)
• Acute Tox. 4 (93.9%)
• STOT SE 3 (95.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.