Description
3-Methoxythiophene-2-carbaldehyde (CAS: 35134-07-7) is a high-purity heterocyclic aldehyde compound with the molecular formula C6H6O2S. This specialized chemical is widely used in organic synthesis, pharmaceutical research, and material science due to its reactive aldehyde functional group and methoxy-substituted thiophene backbone. The product is rigorously tested for quality, ensuring ≥95% purity (HPLC/GC) with minimal impurities, making it ideal for sensitive applications. Available in sealed glass vials under inert gas to prevent degradation, it is supplied with comprehensive analytical data (NMR, MS, FTIR). Suitable for researchers requiring precise intermediates in drug discovery, agrochemical development, and conjugated polymer synthesis.
Properties
- CAS Number: 35134-07-7
- Complexity: 105
- IUPAC Name: 3-methoxythiophene-2-carbaldehyde
- InChI: InChI=1S/C6H6O2S/c1-8-5-2-3-9-6(5)4-7/h2-4H,1H3
- InChI Key: KGJDTMQUUPIAEF-UHFFFAOYSA-N
- Exact Mass: 142.00885060
- Molecular Formula: C6H6O2S
- Molecular Weight: 142.18
- SMILES: COC1=C(SC=C1)C=O
- Topological: 54.5
- Monoisotopic Mass: 142.00885060
- Synonyms: 3-methoxythiophene-2-carbaldehyde, 35134-07-7, DTXSID60343223, DTXCID20294303, 816-222-3, 3-Methoxythiophene-2-carboxaldehyde, 3-methoxy-2-thiophenecarboxaldehyde, MFCD01571098, 2-Thiophenecarboxaldehyde, 3-methoxy-, AI-942/42301781, 3-methoxy-2-thiophenealdehyde, SCHEMBL3245092, SCHEMBL3421374, 3-Methoxy-2-thiophenecarbaldehyde, 3-Methoxy-thiophene-2-carbaldehyde, BCP24382, KBA13407, 3-Methoxy-2-thiophenecarbaldehyde #, GEO-01731, SBB086238, AKOS000280513, PS-3298, SB17763, Thiophene-2-carboxaldehyde, 3-methoxy-, SY026354, DB-069145, CS-0034119, EN300-110080, Z1201621119
3-Methoxythiophene-2-carbaldehyde serves as a key building block in the synthesis of thiophene-based pharmaceuticals and organic electronic materials. It is commonly employed in palladium-catalyzed cross-coupling reactions to create conjugated systems for OLEDs and conductive polymers. Researchers also utilize it as a precursor for Schiff base ligands in coordination chemistry and catalysis. Its stability and reactivity make it valuable in multicomponent reactions for drug candidate libraries.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2A (100%)
- STOT SE 3 (100%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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