Description

3-Iodobenzylamine hydrochloride (CAS No. 3718-88-5) is a high-purity organic compound with the molecular formula C₇H₉ClIN, widely utilized in pharmaceutical and chemical research. This white to off-white crystalline powder is characterized by its iodine-substituted benzylamine structure, making it a valuable intermediate in synthetic organic chemistry. With an IUPAC name of (3-iodophenyl)methanamine;hydrochloride, it offers excellent reactivity for nucleophilic substitution and cross-coupling reactions. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in sealed packaging under inert conditions to maintain stability. Ideal for Suzuki-Miyaura couplings, amide formations, and as a precursor for bioactive molecules.

Properties

• CAS Number: 3718-88-5
• Complexity: 85
• IUPAC Name: (3-iodophenyl)methanamine;hydrochloride
• InChI: InChI=1S/C7H8IN.ClH/c8-7-3-1-2-6(4-7)5-9;/h1-4H,5,9H2;1H
• InChI Key: PYFDZOCGFHIRST-UHFFFAOYSA-N
• Exact Mass: 268.94682
• Molecular Formula: C7H9ClIN
• Molecular Weight: 269.51
• SMILES: C1=CC(=CC(=C1)I)CN.Cl
• Topological: 26
• Monoisotopic Mass: 268.94682
• Synonyms: 3-Iodobenzylamine hydrochloride, Benzenemethanamine, 3-iodo-, hydrochloride, 3-Iodobenzylamine HCl, QMV9MZ6TUU, EINECS 223-068-5, M-IODOBENZYLAMINE HYDROCHLORIDE, DTXSID10190663, Benzylamine, m-iodo-, hydrochloride, BENZENEMETHANAMINE, 3-IODO-, HYDROCHLORIDE (1:1), DTXCID50113154, 223-068-5, 3718-88-5, (3-iodophenyl)methanamine hydrochloride, 3-IodobenzylamineHydrochloride, MFCD00012857, (3-iodophenyl)methanamine;hydrochloride, 3-Iodobenzylamine, HCl, (3-iodophenyl)methylamine, chloride, 3-Iodobenzyl amine HCl, UNII-QMV9MZ6TUU, 3-iodobenzylamine HCl salt, CHEMBL13706, SCHEMBL302630, (3-Iodophenyl)Methanamine HCl, m-iodobenzyl-amine hydrochloride, 3-iodobenzylamine hydrochloride salt, BCP34439, 3-Iodobenzylamine hydrochloride, 97%, AKOS015849389, CS-W002083, DS-1127, FI38588, PS-7287, SY008850, DB-049079, I0710, NS00047326, EN300-1228505, F1967-6740, Z1269220799, 3-Iodobenzylamine HCl;Benzenemethanamine, 3-iodo-, hydrochloride

Application

3-Iodobenzylamine hydrochloride serves as a key building block in medicinal chemistry for the synthesis of iodinated aromatic compounds. It is commonly employed in palladium-catalyzed cross-coupling reactions to create complex pharmaceutical intermediates. Researchers also utilize it for developing radiolabeled probes in imaging studies due to its iodine moiety. Its hydrochloride salt form enhances solubility in polar solvents for ease of handling in organic synthesis.

Safety and Hazards

GHS Hazard Statements

• H315 (97.9%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (87.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H319 (97.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H334 (87.2%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
• H335 (95.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H361 (85.1%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Precautionary Statements

• P203, P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (97.9%)
• Skin Sens. 1 (87.2%)
• Eye Irrit. 2 (97.9%)
• Resp. Sens. 1 (87.2%)
• STOT SE 3 (95.7%)
• Repr. 2 (85.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.