Description
3-Fluorodihydrofuran-2(3H)-one (CAS No. 3885-31-2) is a high-purity fluorinated heterocyclic compound with the molecular formula C4H5FO2. Also known as 3-fluorooxolan-2-one, this specialized chemical is a valuable building block in organic synthesis and pharmaceutical research. The compound features a five-membered lactone ring with a fluorine substituent at the 3-position, offering unique reactivity for nucleophilic substitutions and ring-opening reactions. Our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed containers under inert atmosphere to maintain stability. Suitable for use in medicinal chemistry, agrochemical development, and materials science applications requiring fluorinated intermediates.
Properties
- CAS Number: 3885-31-2
- Complexity: 91.7
- IUPAC Name: 3-fluorotetrahydrofuran-2-one
- InChI: InChI=1S/C4H5FO2/c5-3-1-2-7-4(3)6/h3H,1-2H2
- InChI Key: QSGGLAGTJDEIAN-UHFFFAOYSA-N
- Exact Mass: 104.02735756
- Molecular Formula: C4H5FO2
- Molecular Weight: 104.08
- SMILES: C1COC(=O)C1F
- Topological: 26.3
- Monoisotopic Mass: 104.02735756
- Synonyms: 3-fluorodihydrofuran-2(3H)-one, 3-FLUOROOXOLAN-2-ONE, 3885-31-2, 3-fluoro-dihydrofuran-2(3H)-one, 2(3H)-Furanone, fluorodihydro-, 2-fluorobutyrolactone, 872586-51-1, SCHEMBL577304, 3-Fluorodihydro-2(3H)-furanone, DTXSID90464975, QSGGLAGTJDEIAN-UHFFFAOYSA-N, DTXSID701306191, MFCD26727438, EN300-7329040
Application
3-Fluorodihydrofuran-2(3H)-one serves as a versatile intermediate in the synthesis of fluorinated pharmaceuticals and bioactive molecules. The compound’s reactive lactone ring enables facile derivatization for creating novel heterocyclic systems. Researchers utilize this fluorinated building block in drug discovery programs targeting CNS and anti-inflammatory therapies. The fluorine substitution enhances metabolic stability and bioavailability in resulting compounds, making it particularly valuable for medicinal chemistry applications.
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