Description

(3-Fluoro-4′-pentyl-[1,1′-biphenyl]-4-YL)boronic acid (CAS No. 163129-14-4) is a high-purity boronic acid derivative with the molecular formula C₁₇H₂₀BFO₂. This compound, also known by its IUPAC name [2-fluoro-4-(4-pentylphenyl)phenyl]boronic acid, is a valuable building block in organic synthesis and pharmaceutical research. It features a biphenyl core substituted with a fluorine atom and a pentyl chain, along with a reactive boronic acid group, making it ideal for Suzuki-Miyaura cross-coupling reactions. The product is supplied as a white to off-white crystalline powder with ≥95% purity (HPLC), ensuring consistent performance in sensitive applications. Proper storage under inert conditions (e.g., argon or nitrogen) at 2-8°C is recommended to maintain stability. Suitable for use by researchers in medicinal chemistry, materials science, and catalysis.

Properties

• CAS Number: 163129-14-4
• Complexity: 293
• IUPAC Name: [2-fluoro-4-(4-pentylphenyl)phenyl]boronic acid
• InChI: InChI=1S/C17H20BFO2/c1-2-3-4-5-13-6-8-14(9-7-13)15-10-11-16(18(20)21)17(19)12-15/h6-12,20-21H,2-5H2,1H3
• InChI Key: CCBMYLLGXOKXFX-UHFFFAOYSA-N
• Exact Mass: 286.1540382
• Molecular Formula: C17H20BFO2
• Molecular Weight: 286.2
• SMILES: B(C1=C(C=C(C=C1)C2=CC=C(C=C2)CCCCC)F)(O)O
• Topological: 40.5
• Monoisotopic Mass: 286.1540382
• Synonyms: 163129-14-4, (3-FLUORO-4′-PENTYL-[1,1′-BIPHENYL]-4-YL)BORONIC ACID, 4′-PENTYL-3-FLUOROBIPHENYL-4-BORONIC ACID, [2-fluoro-4-(4-pentylphenyl)phenyl]boronic acid, 3-FLUORO-4′-PENTYLBIPHENYL-4-YLBORONIC ACID, 4”-PENTYL-3-FLUOROBIPHENYL-4-BORONIC ACID, {3-fluoro-4′-pentyl-[1,1′-biphenyl]-4-yl}boronic acid, 4/’/’-PENTYL-3-FLUOROBIPHENYL-4-BORONIC ACID, BORONIC ACID, B-(3-FLUORO-4′-PENTYL[1,1′-BIPHENYL]-4-YL)-, 3-FLUORO-4′-PENTYLBIPHENYL-4-BORONIC ACID, SCHEMBL1533765, DTXSID70696535, CCBMYLLGXOKXFX-UHFFFAOYSA-N, MFCD07368492, AKOS022181862, AB32024, AS-55778, 4′-Pentyl-3-fluoro-biphenyl-4-boronic acid, CS-0447707, (3-Fluoro-4′-pentyl[1,1′-biphenyl]-4-yl)boronic acid, (3-FLUORO-4′-PENTYL-[1,1′-BIPHENYL]-4-YL)BORONICACID

Application

This boronic acid derivative is primarily used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are prevalent in pharmaceuticals and liquid crystal materials. Its fluorine substitution enhances electronic properties, making it valuable for designing drug candidates with improved metabolic stability. The compound is also employed in the development of advanced organic electronic materials and as a ligand in transition metal-catalyzed reactions.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.