Description

3-Fluoro-1-propanol (CAS: 462-43-1) is a high-purity fluorinated alcohol with the molecular formula C₃H₇FO, widely used in pharmaceutical, agrochemical, and materials science research. This versatile compound serves as a key intermediate in organic synthesis, particularly in the preparation of fluorinated derivatives and bioactive molecules. Its unique fluorine substitution enhances reactivity and stability, making it valuable for nucleophilic substitution reactions, cross-coupling chemistry, and as a building block for specialty polymers.

Our product is rigorously tested for purity (>98%) and consistency, ensuring optimal performance in sensitive applications. Available in sealed amber vials or custom bulk quantities, it is stored under controlled conditions to maintain integrity. Ideal for researchers requiring precise fluorination strategies or exploring novel fluorine-containing compounds.

Properties

• CAS Number: 462-43-1
• Complexity: 16.4
• IUPAC Name: 3-fluoropropan-1-ol
• InChI: InChI=1S/C3H7FO/c4-2-1-3-5/h5H,1-3H2
• InChI Key: NLRJUIXKEMCEOH-UHFFFAOYSA-N
• Exact Mass: 78.048093005
• Molecular Formula: C3H7FO
• Molecular Weight: 78.09
• SMILES: C(CO)CF
• Topological: 20.2
• Monoisotopic Mass: 78.048093005
• Synonyms: 3-Fluoro-1-propanol, 1-Propanol, 3-fluoro-, 671-654-8, 3-fluoropropan-1-ol, 462-43-1, 3-Fluoropropanol, Propanol, 3-fluoro-, 3-fluoro-propan-1-ol, MFCD00039548, omega-Fluoropropanol, 3-Hydroxypropyl fluoride, TL 1510, 3-fluoro-propanol, BRN 1731076, 3-Fluoro-1-propanol; 3-Fluoropropanol; 3-Hydroxypropyl Fluoride, 3-fluorpropane-1-ol, 3-fluoropropane-1-ol, SCHEMBL25352, SCHEMBL42496, 4-01-00-01437 (Beilstein Handbook Reference), SCHEMBL5860693, SCHEMBL9175029, CHEMBL4450750, SCHEMBL11780687, SCHEMBL12004411, SCHEMBL18248130, DTXSID90196764, 3-Fluoro-1-propanol, AldrichCPR, AKOS006229996, SY033053, CS-0170820, F1138, EN300-84221

3-Fluoro-1-propanol is employed as a fluorinated synthon in medicinal chemistry for modifying drug candidates to improve metabolic stability. It acts as a solvent or co-solvent in specialty reactions where fluorine incorporation is critical. Additionally, it serves as a precursor for surfactants and liquid crystals in advanced material science applications.

Safety and Hazards

GHS Hazard Statements

• H225 (60%): Highly Flammable liquid and vapor [Danger Flammable liquids]
• H226 (20%): Flammable liquid and vapor [Warning Flammable liquids]
• H301 (20%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (20%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (80%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (80%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H412 (20%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 2 (60%)
• Flam. Liq. 3 (20%)
• Acute Tox. 3 (20%)
• Skin Irrit. 2 (100%)
• Eye Dam. 1 (20%)
• Eye Irrit. 2A (80%)
• STOT SE 3 (80%)
• Aquatic Chronic 3 (20%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.