Atomfair 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid C8H3ClF4O2

Description 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid (CAS No. 129931-45-9) is a high-purity fluorinated benzoic acid derivative with the molecular formula C8H3ClF4O2. This compound is a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty materials. Its unique structure, featuring chloro, fluoro, and trifluoromethyl substituents, enhances reactivity and stability, making it ideal for cross-coupling reactions, nucleophilic substitutions, and other advanced transformations. Available in >98% purity (HPLC), this product is rigorously tested for quality, ensuring consistent performance in research and industrial applications. Suitable for use under inert conditions, it is supplied in sealed packaging to maintain integrity.

Description

3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid (CAS No. 129931-45-9) is a high-purity fluorinated benzoic acid derivative with the molecular formula C₈H₃ClF₄O₂. This compound is a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty materials. Its unique structure, featuring chloro, fluoro, and trifluoromethyl substituents, enhances reactivity and stability, making it ideal for cross-coupling reactions, nucleophilic substitutions, and other advanced transformations. Available in >98% purity (HPLC), this product is rigorously tested for quality, ensuring consistent performance in research and industrial applications. Suitable for use under inert conditions, it is supplied in sealed packaging to maintain integrity.

CAS No: 129931-45-9
Molecular Formula: C8H3ClF4O2
Molecular Weight: 242.55
Exact Mass: 241.9757697
Monoisotopic Mass: 241.9757697
IUPAC Name: 3-chloro-2-fluoro-5-(trifluoromethyl)benzoic acid
SMILES: C1=C(C=C(C(=C1C(=O)O)F)Cl)C(F)(F)F
Synonyms: 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid, 129931-45-9, DTXSID10378686, DTXCID50329713, 630-212-4

Application

3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid is widely used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. Its electron-withdrawing groups facilitate the construction of complex heterocycles and fluorinated compounds. Researchers employ it in Suzuki-Miyaura couplings and as a precursor for herbicides, fungicides, and bioactive molecules. The trifluoromethyl group enhances lipophilicity, making it valuable in drug design for improved metabolic stability.

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