Description

Description

3-Bromoisonicotinic acid (CAS No. 28229-69-8) is a high-purity brominated pyridine carboxylic acid derivative with the molecular formula C₆H₄BrNO₂. This compound, also known by its IUPAC name 3-bromopyridine-4-carboxylic acid, is a versatile building block in pharmaceutical and agrochemical synthesis. The off-white to pale yellow crystalline powder offers >98% purity (HPLC) and is characterized by excellent batch-to-batch consistency. With a molecular weight of 202.01 g/mol, this acid derivative is soluble in polar organic solvents such as DMSO and methanol but exhibits limited water solubility. Proper storage at 2-8??C in a tightly sealed container ensures long-term stability. Each shipment includes comprehensive analytical documentation including ¹H NMR, HPLC, and mass spectrometry data.

Key applications include its use as:

• Precursor for kinase inhibitor development
• Intermediate in heterocyclic compound synthesis
• Building block for metal-organic frameworks (MOFs)
• Starting material for functionalized nicotinic acid derivatives

Application

3-Bromoisonicotinic acid serves as a critical intermediate in medicinal chemistry, particularly in the synthesis of kinase inhibitors and receptor modulators. The compound’s reactive bromine and carboxylic acid groups enable diverse functionalization through cross-coupling reactions and amide bond formation. Researchers utilize this building block in developing novel pharmaceutical candidates targeting inflammatory and oncological pathways. The bromopyridine moiety also finds application in materials science for creating specialized ligands in coordination chemistry.

If you are interested or have any questions, please contact us at support@atomfair.com