Description

Description

3-Bromo-5-iodobenzoic acid (CAS No. 188815-32-9) is a high-purity halogenated benzoic acid derivative with the molecular formula C₇H₄BrIO₂. This compound is a valuable synthetic intermediate for pharmaceutical, agrochemical, and materials science research, featuring both bromo and iodo substituents on the aromatic ring for versatile functionalization. Its carboxyl group enables further derivatization via esterification, amidation, or coupling reactions. Supplied as a white to off-white crystalline powder with ??95% purity (HPLC), it is ideal for cross-coupling reactions (e.g., Suzuki, Sonogashira) and metal-catalyzed transformations. Packaged under inert gas to ensure stability, this product is rigorously tested by GC/MS and ¹H NMR to meet stringent research standards. Store at 2-8??C in a tightly sealed container to prevent degradation.

Application

3-Bromo-5-iodobenzoic acid serves as a key building block in medicinal chemistry for the synthesis of bioactive molecules, particularly in developing kinase inhibitors and PET radiotracers. Its dual halogen functionality allows sequential cross-coupling to construct complex biaryl scaffolds in materials science. Researchers also utilize it as a precursor for liquid crystal intermediates and supramolecular architectures due to its rigid aromatic core and orthogonal reactivity.

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