Description

3-Bromo-4-chloroaniline (CAS No. 823-54-1) is a high-purity halogenated aniline derivative with the molecular formula C₆H₅BrClN. This aromatic amine is a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty dyes. Its unique structure, featuring both bromo and chloro substituents on the aniline ring, enables selective functionalization for complex molecule construction. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a crystalline solid with excellent batch-to-batch consistency. Ideal for Suzuki couplings, Buchwald-Hartwig aminations, and other transition metal-catalyzed reactions. Available in research (5g-100g) and bulk (1kg+) quantities with customizable packaging options. MSDS and analytical certificates provided with every order.

Properties

• CAS Number: 823-54-1
• Complexity: 99.1
• IUPAC Name: 3-bromo-4-chloro-aniline
• InChI: InChI=1S/C6H5BrClN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2
• InChI Key: FVZODFVCIDBDGS-UHFFFAOYSA-N
• Exact Mass: 204.92939
• Molecular Formula: C6H5BrClN
• Molecular Weight: 206.47
• SMILES: C1=CC(=C(C=C1N)Br)Cl
• Topological: 26
• Monoisotopic Mass: 204.92939
• Synonyms: 3-Bromo-4-chloroaniline, 823-54-1, DTXSID90511296, DTXCID40462103, 677-625-6, MFCD00173905, 3-BROMO-4-CHLORO-PHENYLAMINE, 3-Bromo-4-chlorobenzenamine, Benzenamine, 3-bromo-4-chloro-, SCHEMBL459416, SCHEMBL28450476, FVZODFVCIDBDGS-UHFFFAOYSA-N, CL8413, AKOS015920430, CS-W015301, GS-4079, SB78169, AC-28598, FB139556, SY008223, DB-075833, B4160, EN300-103558

Application

3-Bromo-4-chloroaniline serves as a key building block in medicinal chemistry for developing kinase inhibitors and antimicrobial agents. The compound’s halogen pattern makes it valuable for synthesizing liquid crystal materials and OLED intermediates. Researchers utilize it in palladium-catalyzed cross-coupling reactions to create biaryl structures common in pharmaceutical scaffolds.

Safety and Hazards

GHS Hazard Statements

• H302+H312+H332 (80.6%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (97.2%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H332 (97.2%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H373 (88.9%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Precautionary Statements

• P260, P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P319, P321, P330, P362+P364, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Acute Tox. 4 (97.2%)
• Acute Tox. 4 (97.2%)
• STOT RE 2 (88.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.