Description

3-Bromo-2,4-dimethylpyridine (CAS No. 27063-93-0) is a high-purity halogenated pyridine derivative with the molecular formula C₇H₈BrN. This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a bromine substituent at the 3-position and methyl groups at the 2- and 4-positions of the pyridine ring, offering versatile reactivity for cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations.

Our product is rigorously tested for quality, ensuring ≥95% purity (HPLC/GC) with detailed analytical data (NMR, MS) available upon request. Supplied in amber glass vials under inert atmosphere to prevent degradation, it is ideal for sensitive applications. Suitable for use in medicinal chemistry, material science, and as a ligand precursor.

Properties

• CAS Number: 27063-93-0
• Complexity: 94.9
• IUPAC Name: 3-bromo-2,4-dimethyl-pyridine
• InChI: InChI=1S/C7H8BrN/c1-5-3-4-9-6(2)7(5)8/h3-4H,1-2H3
• InChI Key: HWSUJPQZGWOXFZ-UHFFFAOYSA-N
• Exact Mass: 184.98401
• Molecular Formula: C7H8BrN
• Molecular Weight: 186.05
• SMILES: CC1=C(C(=NC=C1)C)Br
• Topological: 12.9
• Monoisotopic Mass: 184.98401
• Synonyms: 3-BROMO-2,4-DIMETHYLPYRIDINE, 27063-93-0, DTXSID80554056, DTXCID80504839, 849-161-6, 3-Bromo-2,4-lutidine, MFCD09842453, Pyridine, 3-bromo-2,4-dimethyl-, SCHEMBL313032, SCHEMBL2872793, 3-bromo-2,4-dimethyl-pyridine, HWSUJPQZGWOXFZ-UHFFFAOYSA-N, AKOS006310449, 3-Bromo-2 pound not4-dimethylpyridine, AB53712, AC-27952, DS-11626, SY105005, DB-067725, CS-0005492, 3-Bromo-2,4-dimethylpyridine;3-Bromo-2,4-lutidine;

Application

3-Bromo-2,4-dimethylpyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. It is widely used in Suzuki-Miyaura and Stille coupling reactions to construct complex heterocycles. Researchers employ this compound in the development of kinase inhibitors and other bioactive molecules due to its pyridine core’s pharmacophoric properties. Its halogen-methyl substitution pattern also makes it valuable for studying regioselective reactions in organic chemistry.

Safety and Hazards

GHS Hazard Statements

• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (50%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.