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Atomfair (3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester C12H16BrNO2

Description (3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester (CAS No. 221538-03-0) is a high-purity organic compound with the molecular formula C12H16BrNO2. This carbamate derivative is widely utilized in pharmaceutical and agrochemical research as a key intermediate in the synthesis of complex molecules. Its IUPAC name, tert-butyl N-(3-bromo-2-methylphenyl)carbamate , reflects its structural composition, featuring a bromo-methylphenyl group protected by a tert-butyl carbamate moiety. The compound is supplied as a crystalline solid with ??95% purity (HPLC), ensuring consistency for sensitive applications. Proper storage at 2-8??C in a tightly sealed container is recommended to maintain stability. This product is ideal for cross-coupling reactions, peptide modifications, and…

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Description

Description

(3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester (CAS No. 221538-03-0) is a high-purity organic compound with the molecular formula C12H16BrNO2. This carbamate derivative is widely utilized in pharmaceutical and agrochemical research as a key intermediate in the synthesis of complex molecules. Its IUPAC name, tert-butyl N-(3-bromo-2-methylphenyl)carbamate, reflects its structural composition, featuring a bromo-methylphenyl group protected by a tert-butyl carbamate moiety. The compound is supplied as a crystalline solid with ??95% purity (HPLC), ensuring consistency for sensitive applications. Proper storage at 2-8??C in a tightly sealed container is recommended to maintain stability. This product is ideal for cross-coupling reactions, peptide modifications, and as a precursor in medicinal chemistry.

  • CAS No: 221538-03-0
  • Molecular Formula: C12H16BrNO2
  • Molecular Weight: 286.16
  • Exact Mass: 285.03644
  • Monoisotopic Mass: 285.03644
  • IUPAC Name: tert-butyl N-(3-bromo-2-methylphenyl)carbamate
  • SMILES: CC1=C(C=CC=C1Br)NC(=O)OC(C)(C)C
  • Synonyms: (3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester, 221538-03-0, MFCD11975627, tert-butyl N-(3-bromo-2-methylphenyl)carbamate, tert-butyl 3-bromo-2-methylphenylcarbamate

Application

(3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester serves as a versatile building block in organic synthesis, particularly in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. Researchers employ this compound to introduce bromo-substituted aromatic systems into target molecules for drug discovery. It is also used in the development of protease inhibitors and kinase modulators due to its carbamate-protected amine functionality. The tert-butyl group enhances solubility in non-polar solvents, facilitating reactions in diverse media.

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